Anti-biofouling Coating Application-Promising Strategy to Prevent Infection

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Microbial Biotechnology".

Deadline for manuscript submissions: closed (30 November 2021) | Viewed by 2022

Special Issue Editor


E-Mail Website
Guest Editor
Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden
Interests: nanomaterials coatings; antimicrobial activity; biofilms; infection; biomedical devices

Special Issue Information

Dear Colleagues,

Biomedical-device-associated infections are considered to be one of the most severe and devastating complications. Such devices or materials in human body are always at risk of microbial colonization and later cause infections, commonly known as device-associated infections. The use of topical or systemic antibiotics is a major treatment strategy for such infections. However, frequent use of such antibiotics is often challenged by the emergence of antibiotic resistance. In this context, antimicrobial coatings on such devices have attracted considerable attention to restrict microbial adhesion or to damage the adhered microbial cells followed by the prevention of associated infections.

The most widely used approach to generate the antifouling properties of biomaterials is coatings of nanomaterials, antimicrobial compounds, hybrid hydrogels, polymers, and drug-loaded hybrid materials. The development of fouling-resistant or self-sterilizing biomaterials is rapidly evolving around the area of surface coatings.

This Special Issue of Microorganisms will present articles associated with the development of biomedical coatings aiming to prevent microbial colonization and associated infections. All manuscripts related to surface coatings with significant antimicrobial efficiency or biofilm inhibitory potential, or reviews on advanced surface coating technologies and their efficiency at preventing infections, are welcome.

Dr. Santosh Pandit
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antimicrobial coatings
  • nanomaterials
  • biomedical devices
  • biofilms
  • antimicrobial polymers
  • antimicrobial drug delivery

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

18 pages, 50409 KiB  
Article
Microbial Adhesion and Biofilm Formation on Bioactive Surfaces of Ti-35Nb-7Zr-5Ta Alloy Created by Anodization
by Laiza Maria Grassi Fais, Luana de Sales Leite, Bárbara Araújo dos Reis, Ana Lúcia Roselino Ribeiro, Luis Geraldo Vaz and Marlise Inêz Klein
Microorganisms 2021, 9(10), 2154; https://0-doi-org.brum.beds.ac.uk/10.3390/microorganisms9102154 - 15 Oct 2021
Cited by 1 | Viewed by 1386
Abstract
This study evaluated the microbial colonization (adhesion and biofilm) on modified surfaces of a titanium alloy, Ti-35Nb-7Zr-5Ta, anodized with Ca and P or F ions, with and without silver deposition. The chemical composition, surface topography, roughness (Ra), and surface free energy were evaluated [...] Read more.
This study evaluated the microbial colonization (adhesion and biofilm) on modified surfaces of a titanium alloy, Ti-35Nb-7Zr-5Ta, anodized with Ca and P or F ions, with and without silver deposition. The chemical composition, surface topography, roughness (Ra), and surface free energy were evaluated before and after the surface modifications (anodizing). Adhesion and biofilm formation on saliva-coated discs by primary colonizing species (Streptococcus sanguinis, Streptococcus gordonii, Actinomyces naeslundii) and a periodontal pathogen (Porphyromonasgingivalis) were assessed. The surfaces of titanium alloys were modified after anodizing with volcano-shaped micropores with Ca and P or nanosized with F, both with further silver deposition. There was an increase in the Ra values after micropores formation; CaP surfaces became more hydrophilic than other surfaces, showing the highest polar component. For adhesion, no difference was detected for S. gordonii on all surfaces, and some differences were observed for the other three species. No differences were found for biofilm formation per species on all surfaces. However, S. gordonii biofilm counts on distinct surfaces were lower than S. sanguinis, A. naeslundii, and P. gingivalis on some surfaces. Therefore, anodized Ti-35Nb-7Zr-5Ta affected microbial adhesion and subsequent biofilm, but silver deposition did not hinder the colonization of these microorganisms. Full article
Show Figures

Figure 1

Back to TopTop