Structural Biology of Phages

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Molecular Microbiology and Immunology".

Deadline for manuscript submissions: closed (30 May 2022) | Viewed by 540

Special Issue Editors


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Guest Editor
Architecture et Fonction des Macromolécules Biologiques, Centre National de la Recherche Scientifique (CNRS), Marseille, France
Interests: bacteriophages structural biology; phage-host interactions; X-ray structure; cryoEM structure
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Co-Guest Editor
Department of Virology, I2BC, CNRS, CEA, University Paris-Saclay, 91190 Saint-Aubin, France
Interests: bacteriophages; virus assembly; phage infection; Gram-positive bacteria

Special Issue Information

Dear Colleagues,

The viruses that infect bacteria—bacteriophages or phages—are the most abundant biological entities on Earth. Phages play an important role in the dynamics of bacterial communities with implications for biogeochemistry, biomes, health (phage therapy), and industry. Phage virions exhibit a broad spectrum of structural morphologies: icosahedral, filamentous, tailed, and pleomorphic particles. Their assembly follows a defined program of sequential protein and protein–nucleic acid interactions. Infectious particles attach specifically to bacterial receptors belonging to various biochemical families, such as surface pro­teins, polysaccharides, and lipopolysaccharides. Therefore, understanding the structure–function relationship of phage particles and the complex dynamics of phage–host interactions is of much interest and requires the exploration of different phage/host couples in addition to the classical model systems.

The last decade has seen a huge amount of progress in our understanding of the structural biology of viral particle structures resulting from advances in X-ray, NMR, cryoEM, and hybrid approaches. The aim of this Special Issue is to provide readers with an update on phage structural biology.

As the Guest Editors of this Special Issue, we invite the submission of research articles, review articles, and short communications on bacteriophage structures, structure–function relationships, and structural aspects of host–phage interactions.

Prof. Christian Cambillau
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers

There is no accepted submissions to this special issue at this moment.
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