Biomineral Inspired Materials for Regenerative Medicine

A special issue of Minerals (ISSN 2075-163X). This special issue belongs to the section "Biomineralization and Biominerals".

Deadline for manuscript submissions: closed (18 October 2022) | Viewed by 1916

Special Issue Editors


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Guest Editor
Laboratory for Biocolloids and Surface Chemistry, Division of Physical Chemistry, Ruđer Bošković Institute, Bijenička Cesta 54, 10000 Zagreb, Croatia
Interests: biomineralization; calcium phosphates; calcium carbonates; nanomaterials; hydrogels; biomimetics; biomaterials; composites

E-Mail Website
Guest Editor
Laboratory for biocolloids and surface chemistry, Division of physical chemistry, Ruđer Bošković Institute, Bijenička Cesta 54,10000 Zagreb, Croatia
Interests: biomaterials; surfactants; nanomaterials; composite materials

E-Mail Website
Guest Editor
Laboratory for Biocolloids and Surface Chemistry, Division of Physical Chemistry, Ruđer Bošković Institute, Bijenička Cesta 54, 10000 Zagreb, Croatia
Interests: calcium phosphates; biomaterials; surfactants; nanomaterials; biomimetics; composite materials
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

It is our pleasure to announce this Special Issue on “Biomineral Inspired Materials for Regenerative Medicine”.

In the field of regenerative medicine, the search for the ideal tissue replacement materials is still ongoing. Current results show that bioinspired materials which mimic natural tissue are among the best candidates for medical applications. Such materials induce a less aversive immune response, especially in comparison with conventional materials. Materials for regenerative medicine should be biocompatible, have similar properties to the tissue they replace, and at the same time be biodegradable, bioinductive, and/or bioconductive. Biomineral inspired application of diverse minerals such as silicates, calcium carbonates, or phosphates is already widespread, but it is hard for a single material to satisfy all the needed requirements. To fulfill the mechanical demands of some materials for regenerative medicine, diverse metallic (stainless steel, CoCE alloys, titanium alloys) or non-metallic inorganic (ceramics, bioactive glasses) materials are being researched. They are commonly combined with diverse organic compounds such as amino acids, proteins, polysaccharides, hormones, drugs, etc. to which the tissue in need of repair should adapt more easily.

We invite you to submit your recent work on the preparation, properties, and applications of biomineral-inspired materials for regenerative medicine for publication in our Special Issue.

Topics of interest for this Special Issue include (but are not limited to):

  • Mineralized hydrogels and scaffolds;
  • Biomaterials as drug delivery devices;
  • Functionalized nanomaterials;
  • Composites.

Dr. Vida Strasser
Dr. Darija Domazet Jurašin
Dr. Maja Dutour Sikirić
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Minerals is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • minerals
  • tissue regeneration
  • bioinspired
  • biomaterials
  • ceramics
  • implant materials
  • composites
  • scaffolds
  • drug delivery devices
  • mineralized hydrogels
  • calcium phosphates
  • calcium carbonates
  • nanomaterials
  • regenerative medicine

Published Papers (1 paper)

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Research

16 pages, 2396 KiB  
Article
Influence of Biomacromolecules on Calcium Phosphate Formation on TiO2 Nanomaterials
by Ina Erceg and Maja Dutour Sikirić
Minerals 2022, 12(12), 1557; https://0-doi-org.brum.beds.ac.uk/10.3390/min12121557 - 02 Dec 2022
Cited by 3 | Viewed by 1310
Abstract
Calcium phosphates (CaP) composites with biomacromolecules and/or nanomaterials have recently emerged as a potential solution to improve the poor mechanical properties and biological response of CaP. Among the methods available for preparation of such composites, precipitation at low temperatures attracts special interest as [...] Read more.
Calcium phosphates (CaP) composites with biomacromolecules and/or nanomaterials have recently emerged as a potential solution to improve the poor mechanical properties and biological response of CaP. Among the methods available for preparation of such composites, precipitation at low temperatures attracts special interest as it allows preservation of the activity of biomacromolecules. However, precipitation of CaP in the presence of two additives is a complex process that needs to be studied in detail to rationalize composite preparation. This study aimed to investigate co-precipitation of CaP on different TiO2 nanomaterials (TiNMs), including nanoparticles (TiNPs), nanoplates (TiNPls), nanotubes (TiNTs), and nanowires (TiNWs), in the presence of bovine serum albumin (BSA) and chitosan (Chi). The obtained results have shown that both BSA and Chi inhibited transformation of amorphous to crystalline CaP, even in the presence of TiNMs at concentrations that promoted transformation. Chi proved to be a stronger inhibitor due to its more flexible structure. The presence of BSA and Chi did not influence the composition of the CaP formed as calcium-deficient hydroxyapatite (CaDHA) was formed in all the systems. However, both macromolecules influenced the morphology of the formed CaDHA in different ways depending on the type of TiNM used. BSA and Chi adsorbed on all the TiNMs, as confirmed by zeta potential measurements, but this adsorption reduced the amount of CaP formed on TiNMs only in the case of TiNWs. The obtained results contribute to the understanding of the influence of BSA and Chi on CaP precipitation in the presence of nanomaterials and thus to the rational design of CaP-based multi-composite materials. Full article
(This article belongs to the Special Issue Biomineral Inspired Materials for Regenerative Medicine)
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