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Green Procedure for Extraction of Bioactive Compounds in Foods and Agricultural by Products

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A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".

Deadline for manuscript submissions: closed (30 September 2022) | Viewed by 14399

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Special Issue Editors

Dr. Rita Celano

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Department of Pharmacy, University of Salerno, Via Giovanni Paolo II 132, 84084 Fisciano, Salerno, Italy
Interests: food chemistry; antioxidants; natural products; mass spectrometry; liquid chromatography; extraction; environmental chemistry
Special Issues, Collections and Topics in MDPI journals

Prof. Dr. Luca Campone

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Department of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza Della Scienza 2, 20126 Milan, Italy
Interests: metabolomic; mass spectrometry; online SPE; liquid chromatography; extraction; food science and safety
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Extraction forms the first basic step in food chemistry research. It represents the starting point for the isolation and purification of chemical constituents present in food matrices. Traditional extraction methods lack selectivity, provide low yields and, due to the high consumption of organic solvents, present safety and environmental risk problems. This special issue focuses on the latest and most innovative approaches for extracting bioactive compounds from foods and agricultural by-products. This collection of manuscripts aims to provide new tools to overcome the classic drawbacks of traditional extraction methods and, above all, to encourage the use of “green” techniques. Manuscripts are also welcome that, through the use of innovative extraction techniques, allow a metabolomic analysis of foods and agricultural by-products.

Dr. Rita Celano
Prof. Dr. Luca Campone
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

Innovative green extraction techniques
Bioactive compounds
Metabolomic analysis
Advanced food technology
Composition of foods
Polyphenol
Flavonoids

Published Papers (3 papers)

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Research

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14 pages, 2053 KiB

Open AccessArticle

Valorisation, Green Extraction Development, and Metabolomic Analysis of Wild Artichoke By-Product Using Pressurised Liquid Extraction UPLC–HRMS and Multivariate Data Analysis

by Stefania Pagliari, Ciro Cannavacciuolo, Rita Celano, Sonia Carabetta, Mariateresa Russo, Massimo Labra and Luca Campone

Molecules 2022, 27(21), 7157; https://0-doi-org.brum.beds.ac.uk/10.3390/molecules27217157 - 22 Oct 2022

Cited by 5 | Viewed by 1480

Abstract

Valorisation of food by-products has recently attracted considerable attention due to the opportunities to improve the economic and environmental sustainability of the food production chain. Large quantities of non-edible parts of the artichoke plant (Cynara cardunculus L.) comprising leaves, stems, roots, bracts, and seeds are discarded annually during industrial processing. These by-products contain many phytochemicals such as dietary fibres, phenolic acids, and flavonoids, whereby the most challenging issue concerns about the recovery of high-added value components from these by-products. The aim of this work is to develop a novel valorisation strategy for the sustainable utilisation of artichoke leaves’ waste, combining green pressurised-liquid extraction (PLE), spectrophotometric assays and UPLC–HRMS phytochemical characterization, to obtain bioactive-rich extract with high antioxidant capacity. Multivariate analysis of the major selected metabolites was used to compare different solvent extraction used in PLE. Full article

(This article belongs to the Special Issue Green Procedure for Extraction of Bioactive Compounds in Foods and Agricultural by Products)

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Review

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21 pages, 1966 KiB

Open AccessReview

Relationship between Immune Cells, Depression, Stress, and Psoriasis: Could the Use of Natural Products Be Helpful?

by Alessio Alesci, Eugenia Rita Lauriano, Angelo Fumia, Natasha Irrera, Enza Mastrantonio, Mario Vaccaro, Sebastiano Gangemi, Antonello Santini, Nicola Cicero and Simona Pergolizzi

Molecules 2022, 27(6), 1953; https://0-doi-org.brum.beds.ac.uk/10.3390/molecules27061953 - 17 Mar 2022

Cited by 36 | Viewed by 7325

Abstract

Psoriasis is one of the most widespread chronic inflammatory skin diseases, affecting about 2%–3% of the worldwide adult population. The pathogenesis of this disease is quite complex, but an interaction between genetic and environmental factors has been recognized with an essential modulation of inflammatory and immune responses in affected patients. Psoriatic plaques generally represent the clinical psoriatic feature resulting from an abnormal proliferation and differentiation of keratinocytes, which cause dermal hyperplasia, skin infiltration of immune cells, and increased capillarity. Some scientific pieces of evidence have reported that psychological stress may play a key role in psoriasis, and the disease itself may cause stress conditions in patients, thus reproducing a vicious cycle. The present review aims at examining immune cell involvement in psoriasis and the relationship of depression and stress in its pathogenesis and development. In addition, this review contains a focus on the possible use of natural products, thus pointing out their mechanism of action in order to counteract clinical and psychological symptoms. Full article

(This article belongs to the Special Issue Green Procedure for Extraction of Bioactive Compounds in Foods and Agricultural by Products)

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14 pages, 617 KiB

Open AccessReview

Green Extraction of Carotenoids from Fruit and Vegetable Byproducts: A Review

by Ewelina Kultys and Marcin Andrzej Kurek

Molecules 2022, 27(2), 518; https://0-doi-org.brum.beds.ac.uk/10.3390/molecules27020518 - 14 Jan 2022

Cited by 38 | Viewed by 4949

Abstract

Carotenoids are characterized by a wide range of health-promoting properties. For example, they support the immune system and wound healing process and protect against UV radiation’s harmful effects. Therefore, they are used in the food industry and cosmetics, animal feed, and pharmaceuticals. The main sources of carotenoids are the edible and non-edible parts of fruit and vegetables. Therefore, the extraction of bioactive substances from the by-products of vegetable and fruit processing can greatly reduce food waste. This article describes the latest methods for the extraction of carotenoids from fruit and vegetable byproducts, such as solvent-free extraction—which avoids the costs and risks associated with the use of petrochemical solvents, reduces the impact on the external environment, and additionally increases the purity of the extract—or green extraction using ultrasound and microwaves, which enables a significant improvement in process efficiency and reduction in extraction time. Another method is supercritical extraction with CO₂, an ideal supercritical fluid that is non-toxic, inexpensive, readily available, and easily removable from the product, with a high penetration capacity. Full article

(This article belongs to the Special Issue Green Procedure for Extraction of Bioactive Compounds in Foods and Agricultural by Products)

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