LC-MS/MS Method for Metabolomics and Proteomics
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Analytical Chemistry".
Deadline for manuscript submissions: closed (15 August 2021) | Viewed by 4278
Special Issue Editor
Interests: metabolomics; LC-MS/MS; HPLC; high resolution mass spectrometry; gas phase ion chemistry; method development; small molecule quantitation; CID; HCD; PRM; chagas diseases; peptide sequencing; fragmentation mechanism; biomarker; liver cancer; photoelectron spectroscopy
Special Issue Information
Dear Colleagues,
The combination of liquid chromatography and mass spectrometry (LC-MS) has been one of the widely used tools of analysis for both chemists and biologists alike for a while now. However, one of the bottlenecks in LC-MS analysis is the lack of available standard methods for assay development (lipids, etc.). This Issue will try to address this by providing a collection of peer-reviewed articles that address LC-MS-related method development for small molecules, both pharmaceutical (drug development, DMPK, toxicology, bio-fluid samples, etc.) and chemical (food science, environmental samples, exposomics etc.) in origin as well as large molecules (e.g., proteins) that are of importance to the biological community and others. The topics of consideration will be method development (involving sample preparation and LC-MS/MS experiments) for analytes related to biomarkers, proteins, antibodies, lipids, nucleic acids, peptides, polymers, peptoids, carbohydrates, natural products, organometallics, small molecules, lichens, drug candidates, pesticides, terpenoids, cannabinoids, forensics, toxicology, and food science for: 1) The discovery of target analytes; 2) Identification and quantitation; 3) Structure elucidation; and 4) Reactivity.
Dr. Ekram Hossain
Guest Editor
Manuscript Submission Information
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Keywords
- proteomics
- metabolomics
- biomarkers
- antibody
- method development
- polymers
- quantitation
- lipids
- structure elucidation
- MRM
- triple quad
- Orbitrap
- HPLC
- LC-MS/MS