Application of Novel Method in Pharmaceutical Study II
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: closed (31 March 2022) | Viewed by 8672
Special Issue Editors
Interests: novel drug delivery system; innovative technologies; microfluidic; targeted therapy; nanotechnology
Special Issues, Collections and Topics in MDPI journals
Interests: nanotechnology; novel nanocarrier; gene therapy; immunotherapy
Special Issue Information
Dear Colleagues,
With the improvements in medical treatment levels, the prevention and treatment of diseases that are difficult to cure have made important progress. Currently, a wide variety of drug formulations and technologies have been explored in malignant tumors, cardio cerebral vascular disease, anti-infection, geriatric diseases, etc. However, a number of problems still need to be solved before their utilization can become routine. These issues include low solubility, poor penetration into cells, hepatic disposition, narrow therapeutic index, rapid uptake by normal tissues, low bioavailability and high costs. Additionally, therapeutic drugs may have unfavorable pharmacokinetic parameters, such as a fast clearance rate and short terminal elimination half-life. Moreover, the emergence of drug resistance involving multiple mechanisms is a major obstacle to successful application in clinics. Therefore, in order to solve these problems, various novel strategies must be applied to pharmaceutical research. These methods include: Nanotechnology for the delivery of drugs, active targeting delivery of drugs for diseases therapy, scientific application of polymer materials and molecular biological methods, and so on.
The purpose of this Special Issue is to present a series of application of novel methods in pharmaceutical study. We are committed to acquiring high-tech drugs that are fixed-time, fixed-position, and quantitative release. We hope these novel methods can help us overcome all the obstacles above.
Prof. Dr. Lesheng Teng
Dr. Zhaogang Yang
Guest Editors
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Keywords
- Nanotechnology
- Targeted therapy
- Novel nanocarrier
- Gene therapy
- Immunotherapy
- Polymer materials