molecules-logo

Journal Browser

Journal Browser

Neuropathic Pain Pharmacology: Efforts to Cure A Deranged, Hyper-Sensitive System

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".

Deadline for manuscript submissions: closed (1 May 2020) | Viewed by 420

Special Issue Editors

Department of Neuroscience, Psychology, Drug Research and Child Health (NEUROFARBA), Pharmacology and Toxicology Section, University of Florence, 50139 Florence, Italy
Interests: pharmacology; medicinal plants; chronic pain; nervous system pathologies and treatment; glia; cholinergic receptors; opioid receptors
Special Issues, Collections and Topics in MDPI journals
Department of Experimental and Clinical Medicine (DMSC), Anatomy Section, School of Human Health Sciences, University of Florence, Florence, Italy
Interests: neuropathic pain; blood–brain barrier; cadmium toxicity; neuroprotection
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Neuropathic pain is a pathology per se. It originates from a lesion or disease of the somatosensory nervous system that evokes dysfuntional, plastic modifications of tissues leading to pain persistence. The maladaptive response of the complex cell network dedicated to the trasmission and perception of pain dramatically upsets nociception as well as the physiological substrate of classical analgesics. A novel way of thinking is necessary to plan and develop effective pain relievers. New targets in sensitive neurons, the relevance of glial cells, and the pivotal role of the central nervous system have emerged in recent years in neuropathic pain physiopathology shedding light into the darkness. Nevertheless, patients need effective drugs to relieve pain and, even more, drugs able to restore the altered nervous system and stop chronicization. Thus, this Special Issue is intended to collect experimental results about innovative approaches and, of course, molecules able to control pain as monotherapy or as adjuvant to other pain killers.

Dr. Lorenzo Di Cesare Mannelli
Dr. Alessandra Pacini
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • pain
  • nociception
  • hyperalgesia
  • allodynia
  • pain relief
  • analgesic
  • pain killer
  • diabetic neuropathy trauma-induced neuropathy
  • chemotherapy-induced neuropathy
  • post-herpetic neuralgia
  • carpal tunnel syndrome
  • maladaptive plasticity
  • hyperexcitability
  • neuron, microglia
  • astrocyte
  • dorsal root ganglia
  • spinal cord
  • pain matrix
  • synthetic molecules
  • antibodies
  • microrna therapeutics
  • sirna
  • natural products

Published Papers

There is no accepted submissions to this special issue at this moment.
Back to TopTop