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Special Issue "Featured Reviews in Natural Products Chemistry"

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".

Deadline for manuscript submissions: 30 September 2021.

Special Issue Editors

Dr. Enrique Barrajon
E-Mail Website
Guest Editor
Institute of Research, Development and Innovation in Healthcare Biotechnology of Elche (IDiBE), Miguel Hernández University (UMH), Alicante, Spain
Interests: natural compounds; polyphenols; marine compounds; cancer; antimicrobial; skin; cosmetics
Special Issues and Collections in MDPI journals
Prof. Dr. Vicente Micol
E-Mail Website
Guest Editor
Instituto de Investigación, Desarrollo e Innovación en Biotecnologia Sanitaria at Miguel Hernández University, Elche, Spain
Interests: natural compounds; polyphenols; metabolic disorders; obesity; cancer; antimicrobial; skin; cosmetics
Special Issues and Collections in MDPI journals
Prof. Dr. María Herranz-López
E-Mail Website
Guest Editor
Instituto de Investigación, Desarrollo e Innovación en Biotecnologia Sanitaria at Miguel Hernández University, Elche, Spain
Interests: metabolic disorders; inflammation; bioactive compounds; cancer; cell death
Special Issues and Collections in MDPI journals

Special Issue Information

Dear Colleagues,

Natural compounds from animal, microbial, vegetal, or fungi origin represent countless sources of new compounds that can be used as novel drugs if their activity, bioavailability, and toxicity are adequate.

The literature contains plenty of examples covering most of the more relevant diseases that have been treated using a plethora of chemical structures and extraction methods for compounds of natural origin. Furthermore, many actual drugs are based on natural compounds, pointing out the importance of natural compounds in novel drug discovery.

This Special Issue aims to compile reviews covering the most recent advances in the use of natural compounds in any scientific fields, with special emphasis on metabolic disorders, cancer, antimicrobials development, and cosmetics. Reviews covering extractive methods or “omic” techniques are also welcome.

Dr. Enrique Barrajon
Prof. Dr. Vicente Micol
Prof. Dr. María Herranz-López
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • natural products
  • polyphenols
  • carotenoids
  • metabolic disorders
  • antimicrobials
  • cancer
  • cosmetics  

Published Papers (1 paper)

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Review

Review
Plant-Based Indole Alkaloids: A Comprehensive Overview from a Pharmacological Perspective
Molecules 2021, 26(8), 2297; https://0-doi-org.brum.beds.ac.uk/10.3390/molecules26082297 - 15 Apr 2021
Cited by 1 | Viewed by 560
Abstract
Plant-based indole alkaloids are very rich in pharmacological activities, and the indole nucleus is considered to contribute greatly to these activities. This review’s fundamental objective is to summarize the pharmacological potential of indole alkaloids that have been derived from plants and provide a [...] Read more.
Plant-based indole alkaloids are very rich in pharmacological activities, and the indole nucleus is considered to contribute greatly to these activities. This review’s fundamental objective is to summarize the pharmacological potential of indole alkaloids that have been derived from plants and provide a detailed evaluation of their established pharmacological activities, which may contribute to identifying new lead compounds. The study was performed by searching various scientific databases, including Springer, Elsevier, ACS Publications, Taylor and Francis, Thieme, Wiley Online Library, ProQuest, MDPI, and online scientific books. A total of 100 indole compounds were identified and reviewed. The most active compounds possessed a variety of pharmacological activities, including anticancer, antibacterial, antiviral, antimalarial, antifungal, anti-inflammatory, antidepressant, analgesic, hypotensive, anticholinesterase, antiplatelet, antidiarrheal, spasmolytic, antileishmanial, lipid-lowering, antimycobacterial, and antidiabetic activities. Although some compounds have potent activity, some only have mild-to-moderate activity. The pharmacokinetic profiles of some of the identified compounds, such as brucine, mitragynine, 7-hydroxymitragynine, vindoline, and harmane, were also reviewed. Most of these compounds showed promising pharmacological activity. An in-depth pharmacological evaluation of these compounds should be performed to determine whether any of these indoles may serve as new leads. Full article
(This article belongs to the Special Issue Featured Reviews in Natural Products Chemistry)
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