Synthesis and Properties of Macrocyclic Compound
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Organic Chemistry".
Deadline for manuscript submissions: closed (31 July 2021) | Viewed by 14992
Special Issue Editor
Interests: macrocyclic chemistry; heterocycles; structural/physical organic chemistry; bioorganic chemistry; functional solid-state chemistry
Special Issue Information
Dear Colleagues,
Starting with cyclophanes, which were synthesized in the early 1950s, macrocyclic compounds have won Nobel prizes for bicyclic amines, crown ethers, and cryptands. Even today, catenanes, rotaxanes, and self-assembled molecules are special topics of chemistry. In recent structural chemistry, the world of macrocyclic compounds plays an important role.
In this case, the nitrogen atom is useful in the synthesis of host compounds with a three-dimensional structure, characterized by its trivalent nature, simple and wide range of synthesis methods, and electron lone pairs. This allows for the synthesis of azacrown ethers, cryptands, etc. Furthermore, by properly arranging the nitrogen atoms in space, their basicity can be increased tens of thousands of times. In a manner of speaking, the proton sponge was born. With such precise molecular design, research on special compounds that take advantage of the properties of atoms has become more and more popular.
In this special issue, we invite original papers and timely reviews on the synthesis, structure, and properties of macrocyclic compounds with special properties.
This special issue is not limited to the chemistry of nitrogen bridging compounds. Papers on a variety of cyclic compounds are invited.
All research topics related to the chemistry of cyclic compounds are welcome.
Prof. Dr. Hiroyuki Takemura
Guest Editor
Keywords
- macocycles
- cyclophane
- cryptand
- crown ether
- proton sponge
- cage compound