Oxidative Stress as a Pharmacological Target for Medicinal Chemistry
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: closed (28 February 2022) | Viewed by 26718
Special Issue Editors
Interests: oxidative stress; antioxidants; ROS/RNS; flavonoids; chromones; mass spectrometry; antioxidant enzymes; metabolism
Special Issues, Collections and Topics in MDPI journals
Interests: hyphenated techniques; organic synthesis; heterocyclic chemistry; separation; extraction; purification
Special Issues, Collections and Topics in MDPI journals
Interests: heart; ischemia/reperfusion; heme oxygenase-1; autophagy; natural antioxidants
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
It is well known that oxidative stress is one of the major factors contributing in the development of several chronic diseases such as cardiovascular disorders, cancer, different neurodegenerative diseases, diabetes, and aging. The reduction of oxidative stress-caused damages is essential in effective prevention and/or treatment of these types of pathologies. The impaired balance between the antioxidant defense mechanisms and the pro-oxidant processes can be restored either by increasing the former or decreasing the latter.
This Special Issue may cover all aspects of the oxidative stress-related research. Original research papers as well as review articles are welcomed on the synthesis, derivatization, extraction, purification, and structural analysis of possible new antioxidants, their biological evaluation, and mechanisms of action. Furthermore, studies of new exogenous or endogenous modulators of oxidative stress in different oxidative stress-related disease models are also welcomed.
Dr. Istvan BakDr. Attila Kiss
Dr. Istvan Lekli
Guest Editors
Keywords
- Oxidative stress
- ROS/RNS
- Antioxidants
- Synthesis
- Extraction
- Structural analysis
- Pharmacology
- Antioxidant enzymes
- Autophagy