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Silica Surfaces and Their Modifications for Analytical Chemistry

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Molecular Structure".

Deadline for manuscript submissions: closed (30 November 2021) | Viewed by 5582

Special Issue Editor


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Guest Editor
Chair of Environmental Chemistry and Bioanalytics, Faculty of Chemistry, Nicolaus Copernicus University in Toruń, 7 Gagarin St., 87-100 Toruń, Poland
Interests: liquid chromatography (HPLC, UPLC); analytical chemistry; stationary phases synthesis and characterization; surface phenomena in liquid chromatography; solvation processes; retention mechanism in RP LC, HILIC, PALC; purely aqueous separation

Special Issue Information

Dear Colleagues,

Silica gel is the most common material applied as a column packing for liquid chromatography. It may be used as an adsorbent for normal phase chromatography and in hydrophilic interaction liquid chromatography. Silica gel may be also modified to obtain chemically bonded stationary phases with hydrophobic or hydrophilic functional groups for reversed phase chromatography. These modifications that may be carried out in different methodologies allow to obtain expected surface properties of the stationary phases, dedicated to specific chromatographic mode and offer unusual selectivity. Despite of liquid chromatography, silica gel and its modifications are commonly applied for materials used for sample preparation, extraction, purification, ect.

The main aim of the Special Issue on "Silica Surfaces and Their Modifications for Analytical Chemistry" is to be an open forum where researchers may share their investigations and findings in this still evolving field and, due to the open access platform, increase their visibility. Contributions to this issue, both in the form of original research and review articles, may cover all aspects of production, modification, characterization and application of silica materials in analytical chemistry, are particularly welcome.

Prof. Dr. Szymon Bocian
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Silica gel
  • Silica surface modification
  • Separation techniques
  • Stationary phases
  • Chromatography
  • Extraction techniques
  • Sample preparation

Published Papers (2 papers)

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Research

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11 pages, 972 KiB  
Article
Solvent Influence on Zeta Potential of Stationary Phase—Mobile Phase Interface
by Mikołaj Dembek, Szymon Bocian and Bogusław Buszewski
Molecules 2022, 27(3), 968; https://0-doi-org.brum.beds.ac.uk/10.3390/molecules27030968 - 31 Jan 2022
Cited by 22 | Viewed by 2713
Abstract
Zeta potential is a surface characteristic formed on the solid surface and liquid interface. It is an interesting way to describe the surface properties of materials; thus, a series of four homemade polar embedded stationary phases that contain phosphate groups incorporated into hydrophobic [...] Read more.
Zeta potential is a surface characteristic formed on the solid surface and liquid interface. It is an interesting way to describe the surface properties of materials; thus, a series of four homemade polar embedded stationary phases that contain phosphate groups incorporated into hydrophobic ligands were investigated according to surface zeta potential. Measurements were carried out using Zetasizer Nano ZS for the stationary phases suspensions prepared in various solvent and solvent binary mixtures. The negative zeta potential values were obtained for most cases due to negatively charged residual silanols and phosphate groups. However, in some solvents: tetrahydrofuran, isopropanol, and toluene zeta potential are positive. Additionally, it was observed that the zeta potential seems to be independent of the type of silica gel used for the stationary phase synthesis. Full article
(This article belongs to the Special Issue Silica Surfaces and Their Modifications for Analytical Chemistry)
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Review

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16 pages, 1686 KiB  
Review
Silica Hydride: A Separation Material Every Analyst Should Know About
by Joseph J. Pesek and Maria T. Matyska
Molecules 2021, 26(24), 7505; https://0-doi-org.brum.beds.ac.uk/10.3390/molecules26247505 - 11 Dec 2021
Cited by 3 | Viewed by 2309
Abstract
This review describes the development, special features and applications of silica hydride-based stationary phases for HPLC. The unique surface of this material is in contrast to ordinary, standard silica, which is the material most frequently used in modern HPLC stationary phases. The standard [...] Read more.
This review describes the development, special features and applications of silica hydride-based stationary phases for HPLC. The unique surface of this material is in contrast to ordinary, standard silica, which is the material most frequently used in modern HPLC stationary phases. The standard silica surface contains mainly silanol (Si-OH) groups, while the silica hydride surface is instead composed of silicon-hydrogen groups, which is much more stable, less reactive and delivers different chromatographic and chemical characteristics. Other aspects of this material are described for each of the different bonded moieties available commercially. Some applications for each of these column types are also presented as well as a generic model for method development on silica hydride-based stationary phases. Full article
(This article belongs to the Special Issue Silica Surfaces and Their Modifications for Analytical Chemistry)
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