Coordination Chemistry in Cancer Therapy
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: 31 May 2024 | Viewed by 13191
Special Issue Editors
Interests: analytical chemistry; metal complexes; drug design; chemometrics; artificial neural network; experimental design
Special Issue Information
Dear Colleagues,
As guest editor, it is my pleasure to announce the launch of a Special Issue entitled “Coordination Chemistry in Cancer Therapy”.
Metal-based coordination compounds have been exploited in cancer therapy since the discovery of cisplatin in 1965, and in fact, a great number of metal complexes with platinum, ruthenium, gold or copper have been prepared and tested. Different effects have been exploited, from catalytic ones, to reactive oxygen species generation, radio frequency ablation, use of scaffold, photodynamic therapy, and so on, all with the intent to properly tune cytotoxicity, selectivity, synergy and biocompatibility. In many cases, action mechanisms are still unrevealed, as well as the composite relationships between homeostasis of cellular compartment and cancer development; however, a deep study of targets, delivery routes, bio-chemical reactions, and physicochemical properties of the most promising metal complexes are helpful to design and rationally develop advanced and safe drugs, to be used alone or in combination.
This Special Issue devoted to the study of metal complexes in cancer therapy will collect communications, research articles, and high-quality review papers in research fields relating to chemical biology.
I kindly encourage all research groups working in this field to contribute to this Special Issue involving, but not restricted to: metal-based drug design, synthesis and test; target identification of metal-based anticancer drug; and the study of mechanism of action of the most promising metal complexes as anticancer agents. Theoretical studies are also welcome.
Prof. Dr. Tiziana Pivetta
Dr. Sarah Vascellari
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- metal-based anticancer drug
- coordination chemistry
- anticancer drug design
- action mechanism
- cancer therapy
- combination therapy
- QSAR
- molecular docking
