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What Is Next for Antibacterial Materials
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What Is Next for Antibacterial Materials

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Materials Chemistry".

Deadline for manuscript submissions: closed (15 August 2021) | Viewed by 5703

Special Issue Editor

Dr. Pascal Thebault

E-Mail Website
Guest Editor
Université de Rouen Normandie, Mont-Saint-Aignan, France
Interests: surface modification; antibacterial surfaces; surface characterization; functional polymers; antimicrobial peptides

Special Issue Information

Dear Colleagues,

For a long time, the bacterial contamination of surfaces, leading to biofilm formation, has been a major problem in fields as diverse as medical, food or cosmetics, and despite the use and development of preventive hygiene protocols. In order to eliminate or reduce bacterial colonization of surfaces and biofilm formation, many strategies have emerged. The two main approaches are (i) to repel bacteria and (ii) to kill bacteria but neither antiadhesive nor bactericidal surfaces have yet allowed us to win the battle against bacterial contamination. This Special Issue aims to identify the latest advances and the future in the race for the perfect antibacterial material.

Dr. Pascal Thebault
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Antibacterial materials
  • Smart surfaces
  • Natural compounds
  • Stimuli-responsive materials
  • Dual-function surfaces
  • Surfaces modification

Published Papers (2 papers)

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Research

24 pages, 6285 KiB  
Article
Modified Nanofibrous Filters with Durable Antibacterial Properties
by Ganna Ungur and Jakub Hrůza
Molecules 2021, 26(5), 1255; https://0-doi-org.brum.beds.ac.uk/10.3390/molecules26051255 - 26 Feb 2021
Cited by 7 | Viewed by 1834
Abstract
The main aims of the research were to produce efficient nanofibrous filters with long-term antibacterial properties and to confirm the functionality of samples under real filtration conditions. A polyurethane solution was modified by micro- or nanoparticles of copper oxide in order to juxtapose [...] Read more.
The main aims of the research were to produce efficient nanofibrous filters with long-term antibacterial properties and to confirm the functionality of samples under real filtration conditions. A polyurethane solution was modified by micro- or nanoparticles of copper oxide in order to juxtapose the aggregation tendency of particles depending on their size. Modified solutions were electrospun by the Nanospider technique. The roller spinning electrode with a needle surface and static wire electrode were used for the production of functionalized nanofibers. The antibacterial properties of the modified nanofibrous layers were studied under simulated conditions of water and air filtration. Particular attention was paid to the fixation mechanism of modifiers in the structure of filters. It was determined that the rotating electrode with the needle surface is more efficient for the spinning of composite solutions due to the continuous mixing and the avoidance of particle precipitation at the bottom of the bath with modified polyurethane. Moreover, it was possible to state that microparticles of copper oxide are more appropriate antimicrobial additives due to their weaker aggregation tendency but stronger fixation in the fibrous structure than nanoparticles. From the results, it is possible to conclude that nanofibers with well-studied durable antibacterial properties may be recommended as excellent materials for water and air filtration applications. Full article
(This article belongs to the Special Issue What Is Next for Antibacterial Materials)
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16 pages, 2052 KiB  
Article
Biogenic Gold Nanoparticles Decrease Methylene Blue Photobleaching and Enhance Antimicrobial Photodynamic Therapy
by Irena Maliszewska, Ewelina Wanarska, Alex C. Thompson, Ifor D. W. Samuel and Katarzyna Matczyszyn
Molecules 2021, 26(3), 623; https://0-doi-org.brum.beds.ac.uk/10.3390/molecules26030623 - 25 Jan 2021
Cited by 31 | Viewed by 3491
Abstract
Antibiotic resistance is a growing concern that is driving the exploration of alternative ways of killing bacteria. Here we show that gold nanoparticles synthesized by the mycelium of Mucor plumbeus are an effective medium for antimicrobial photodynamic therapy (PDT). These particles are spherical [...] Read more.
Antibiotic resistance is a growing concern that is driving the exploration of alternative ways of killing bacteria. Here we show that gold nanoparticles synthesized by the mycelium of Mucor plumbeus are an effective medium for antimicrobial photodynamic therapy (PDT). These particles are spherical in shape, uniformly distributed without any significant agglomeration, and show a single plasmon band at 522–523 nm. The nanoparticle sizes range from 13 to 25 nm, and possess an average size of 17 ± 4 nm. In PDT, light (from a source consisting of nine LEDs with a peak wavelength of 640 nm and FWMH 20 nm arranged in a 3 × 3 array), a photosensitiser (methylene blue), and oxygen are used to kill undesired cells. We show that the biogenic nanoparticles enhance the effectiveness of the photosensitiser, methylene blue, and so can be used to kill both Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli) bacteria. The enhanced effectiveness means that we could kill these bacteria with a simple, small LED-based light source. We show that the biogenic gold nanoparticles prevent fast photobleaching, thereby enhancing the photoactivity of the methylene blue (MB) molecules and their bactericidal effect. Full article
(This article belongs to the Special Issue What Is Next for Antibacterial Materials)
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