Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
6.7
4.6
Journals
Molecules
Special Issues
Main Elements in Organic Synthesis: A Themed Issue in Honor...
molecules-logo
Submit to Molecules Review for Molecules Propose a Special Issue

Journal Menu

► Journal Menu

Journal Browser

► Journal Browser
share announcement

Main Elements in Organic Synthesis: A Themed Issue in Honor of Professor Jozef Drabowicz

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Organic Chemistry".

Deadline for manuscript submissions: closed (30 November 2023) | Viewed by 2231

Special Issue Editors

Prof. Dr. Claudio Santi

E-Mail Website
Guest Editor
Group of Catalysis and Organic Grenn Chemistry, Department of Pharmaceutical Sciences, University of Perugia, 06123 Perugia, PG, Italy
Interests: selenium; catalysis; green chemistry; flow chemistry; synthetic methodologies; redox; complexity
Special Issues, Collections and Topics in MDPI journals
Dr. Luca Sancineto

E-Mail Website
Guest Editor
Department of Pharmaceutical Sciences, Group of Catalysis, Synthesis and Organic Green Chemistry, University of Perugia, Perugia, Italy
Interests: organic synthesis; medicinal chemistry; selenium compounds
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

When we accepted to edit a special issue dedicated to the career of prof Jozef Drabowicz, in the year of his 75th birthday, we decided to choose a topic broad enough to attract manuscripts that should be representative of his large and eclectic scientific interests and scientific contribution in the field of organic chemistry. Original research articles and review articles dealing with the elements of the main groups in organic synthesis, with particular emphasis on the chemistry of chalcogens, halogens and phosphorous will be welcome. A special invitation to contribute is directed, but not limited, to all the scientists, colleagues and friends that had the opportunity to be supervised, to collaborate or to be inspired by prof Drabowicz.

Prof. Dr. Claudio Santi
Dr. Luca Sancineto
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • selenium
  • sulphur
  • halogens
  • phosphorous
  • boron
  • asymmetric synthesis

Published Papers (1 paper)

Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

12 pages, 2593 KiB  
Article
Electrophile-Dependent Reactivity of Lithiated N-Benzylpyrene-1-Carboxamide
by Magdalena Ciechańska, Anna Wrona-Piotrowicz, Karolina Koprowska, Anna Makal and Janusz Zakrzewski
Molecules 2022, 27(12), 3930; https://0-doi-org.brum.beds.ac.uk/10.3390/molecules27123930 - 19 Jun 2022
Viewed by 1344
Abstract
In this paper, we describe the lithiation of N-benzylpyrene-1-carboxamide with RLi-TMEDA. We found that the reaction outcome strongly depends on the electrophile used in the quenching step. The electrophile can be introduced at either the benzylic position or at the C-2 position [...] Read more.
In this paper, we describe the lithiation of N-benzylpyrene-1-carboxamide with RLi-TMEDA. We found that the reaction outcome strongly depends on the electrophile used in the quenching step. The electrophile can be introduced at either the benzylic position or at the C-2 position in the pyrene nucleus. Furthermore, when H+ was used as the quencher, the product of the intramolecular carbolithiation of the pyrene K-region was formed. Dehydrogenation of the obtained compound with DDQ allowed the synthesis of a novel nitrogen polycyclic compound with an aza-benzo[c,d]pyrene (azaolympicene) skeleton. Attempts to extend the reaction scope to the amides substituted in the phenyl ring 8a and 8b gave an unexpected result. The reaction of both compounds with BuLi gave 1-valerylpyrene (9) in good yield. Photophysical properties, including absorption spectra, emission spectra and quantum yields of the emission of selected products, were studied and discussed. Full article
(This article belongs to the Special Issue Main Elements in Organic Synthesis: A Themed Issue in Honor of Professor Jozef Drabowicz)
►▼ Show Figures

Graphical abstract

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-1
Back to TopTop