Advances in Nanotoxicology and Nano-Safety

A special issue of Nanomaterials (ISSN 2079-4991). This special issue belongs to the section "Biology and Medicines".

Deadline for manuscript submissions: closed (27 January 2023) | Viewed by 2840

Special Issue Editor


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Guest Editor
Institute of Geosciences (Spanish Council of Research (CSIC), Complutense University of Madrid), Madrid, Spain
Interests: nano-scale phase transformation processes; multifunctional nanomaterials; alternative safe nano-synthesis methods; building materials; heritage conservation (photocatalytic, consolidant, hydrophobic, hydrophilic, flame retardant, or anti-fungal); petrology; mineralogy; crystallography; latest-generation characterization techniques; natural-origin nanomaterials and tracing methods; multifunctional nanomaterials; nano-risks; nano-safety; nano-prevention; alternative synthesis; handling; environmental risks; tracing methods; building materials; natural-origin nanomaterials
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Special Issue Information

Dear Colleagues,

Nanotechnology has come a long way in the last two decades. Its wide diversity of applications covering areas as diverse as medicine, industrial processes, electronics, cosmetics, agriculture, food, metallurgy, and construction materials can carry risks that remain unknown. Its effects on living beings and the environment constitute a new factor that has increasingly attracted attention over the years, giving rise to nanotoxicology. Since the first toxicity effects we realized, a new generation of hybrid nanomaterials developed and the lack of knowledge seems to be even greater. To date, there is significant uncertainty of its nanotoxicology aspects regarding specific properties. Additionally, the relevant factors related to the handling of nanomaterials and their subsequent staging continually grow. Fortunately, international associations have intensified their efforts in gathering information to lessen the possible risks and improve nano-prevention knowledge. It is essential to maintain a constant contribution to the progress based on new diagnostic tools. Exposure to nanomaterials is one of the primary reasons of death, even from prenatal ages. Today, the impact of new nanomaterials is unknown. Given the magnitude of the toxicity risks, it is urgent to elucidate its effects on living beings and the environment. The possible implications at the cardiovascular, pulmonary, or neurological level must be uncovered, and the problem must tackled from the early stages of nanomaterial synthesis by opting for safe alternative methods. There is, thus, an urgent need to report the advances in the evaluation of nanoengineered materials, realizing their effects at the organism and cellular level, including the consequences of their environmental exposure.

Dr. Luz Stella Gomez-Villalba
Guest Editor

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nanomaterials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nanomaterials
  • nanofibers
  • nanotoxicity
  • nano-oxides
  • MWCNT
  • growth mechanisms and cell damage
  • neuronal, pulmonary, cardiovascular, and gastrointestinal diseases
  • perinatal and prenatal risk
  • dental materials
  • ocular and skin exposure
  • nano-additives in food and cosmetics
  • environmental pollution
  • nano-safety
  • eco-friendly synthesis methods
  • building and fine arts materials
  • mining
  • industrial waste
  • geological emissions
  • electronic and industrial products

Published Papers (2 papers)

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Research

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14 pages, 2513 KiB  
Article
Effect and Mechanism of PINK1/Parkin-Mediated Mitochondrial Autophagy in Rat Lung Injury Induced by Nano Lanthanum Oxide
by Chunyu Chen, Chenxi Zhou, Wenli Zhang, Haiping Liu, Mengfei Wang, Feng Li, Qingzhao Li and Yanhua Cao
Nanomaterials 2022, 12(15), 2594; https://0-doi-org.brum.beds.ac.uk/10.3390/nano12152594 - 28 Jul 2022
Cited by 6 | Viewed by 1345
Abstract
Nano lanthanum oxide particles (La2O3 NPs) are important nanoparticle materials which are widely used in photoelectric production, but their potential health hazards to the respiratory system are not clear. The purpose of this study was to explore the possible mechanism [...] Read more.
Nano lanthanum oxide particles (La2O3 NPs) are important nanoparticle materials which are widely used in photoelectric production, but their potential health hazards to the respiratory system are not clear. The purpose of this study was to explore the possible mechanism of lung injury induced by La2O3 NPs. In this study, 40 SPF male SD rats were randomly divided into low-, medium-, and high-dose groups and control groups, with 10 animals in each group. Rats were poisoned by tracheal injection. The low-, medium-, and high-dose groups were given La2O3 NPs suspension of 25, 50, and 100 mg/kg, respectively, and the control group was given an equal volume of high-temperature sterilized ultrapure water. The rats in each group were exposed once a week for 12 consecutive times. The gene transcription and protein expression levels of PINK1 and parkin in rat lung tissue were mainly detected. Compared with the control group, the gene transcription and protein expression levels of PINK1 and Parkin in the exposed group were significantly higher (p < 0.05). La2O3 NPs may activate PINK1/parkin-induced mitochondrial autophagy. Full article
(This article belongs to the Special Issue Advances in Nanotoxicology and Nano-Safety)
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Review

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74 pages, 4947 KiB  
Review
Application of Inorganic Nanomaterials in Cultural Heritage Conservation, Risk of Toxicity, and Preventive Measures
by Luz Stella Gomez-Villalba, Ciro Salcines and Rafael Fort
Nanomaterials 2023, 13(9), 1454; https://0-doi-org.brum.beds.ac.uk/10.3390/nano13091454 - 24 Apr 2023
Cited by 7 | Viewed by 2912
Abstract
Nanotechnology has allowed for significant progress in architectural, artistic, archaeological, or museum heritage conservation for repairing and preventing damages produced by deterioration agents (weathering, contaminants, or biological actions). This review analyzes the current treatments using nanomaterials, including consolidants, biocides, hydrophobic protectives, mechanical resistance [...] Read more.
Nanotechnology has allowed for significant progress in architectural, artistic, archaeological, or museum heritage conservation for repairing and preventing damages produced by deterioration agents (weathering, contaminants, or biological actions). This review analyzes the current treatments using nanomaterials, including consolidants, biocides, hydrophobic protectives, mechanical resistance improvers, flame-retardants, and multifunctional nanocomposites. Unfortunately, nanomaterials can affect human and animal health, altering the environment. Right now, it is a priority to stop to analyze its advantages and disadvantages. Therefore, the aims are to raise awareness about the nanotoxicity risks during handling and the subsequent environmental exposure to all those directly or indirectly involved in conservation processes. It reports the human–body interaction mechanisms and provides guidelines for preventing or controlling its toxicity, mentioning the current toxicity research of main compounds and emphasizing the need to provide more information about morphological, structural, and specific features that ultimately contribute to understanding their toxicity. It provides information about the current documents of international organizations (European Commission, NIOSH, OECD, Countries Normative) about worker protection, isolation, laboratory ventilation control, and debris management. Furthermore, it reports the qualitative risk assessment methods, management strategies, dose control, and focus/receptor relationship, besides the latest trends of using nanomaterials in masks and gas emissions control devices, discussing their risk of toxicity. Full article
(This article belongs to the Special Issue Advances in Nanotoxicology and Nano-Safety)
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