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Nanomaterials
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Frontiers in Nanopore-Based Analytics
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Frontiers in Nanopore-Based Analytics

A special issue of Nanomaterials (ISSN 2079-4991). This special issue belongs to the section "Synthesis, Interfaces and Nanostructures".

Deadline for manuscript submissions: closed (30 November 2022) | Viewed by 3925

Special Issue Editors

Prof. Dr. Yongdong Jin

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Guest Editor
State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China
Interests: nanopore-based analytics; single cell studies; plasmonic nanostructures and applications; bio-nano interface and nanomedicine
Prof. Dr. Haijuan Li

E-Mail Website
Guest Editor
State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China
Interests: electrochemical sensors; bio-nano interface; electrocatalysis; plasmonic nanostructures and applications

Special Issue Information

Dear Colleagues,

Nanopores, that is, nanoscale pores, have the inherent characteristics of high sensitivity and high spatial resolution and, therefore, have broad application prospects in sensing and analysis. It is generally considered an indispensable platform and tool in the research field of fundamental ion transport and molecular sensing. Thus far, nanopore analytics, based either on solid-state nanopores or biological nanopores and their hybrids, have offered versatile platforms for testing fundamental concepts of molecular stochasticity and ionic transport at the nanoscale, for studying single-molecule biophysics, and also for new analytical applications in biomedical sensing.

The goal of this Special Issue is to collect publications focused on promising and novel research trends in the field of nanopore-based analytics. We welcome submissions of original research, reviews, mini reviews, and perspective articles. Themes of particular interest include:

  1. Construction of novel nanopore-based platforms and analytics for sensitive sensing of single molecules, single particles, and single cells;
  2. The exploration of new methods and strategies of nanopore-based analytics and their innovative sensing applications;
  3. Data analysis and theoretical simulations of nanopore-based molecular and/or ionic transport studies.

Prof. Dr. Yongdong Jin
Prof. Dr. Haijuan Li
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nanomaterials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Biological nanopore
  • Solid-state nanopore
  • Sensing and biosensing
  • Nanopore-based nanofluidics
  • Single-cell study
  • Nanopore analytics

Published Papers (2 papers)

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Research

13 pages, 2312 KiB  
Article
Study Effect of nAg Particle Size on the Properties and Antibacterial Characteristics of Polysulfone Membranes
by Gunawan Setia Prihandana, Tutik Sriani, Aisyah Dewi Muthi’ah, Affiani Machmudah, Muslim Mahardika and Norihisa Miki
Nanomaterials 2022, 12(3), 388; https://0-doi-org.brum.beds.ac.uk/10.3390/nano12030388 - 25 Jan 2022
Cited by 18 | Viewed by 2447
Abstract
Polysulfone ultrafiltration membranes were fabricated using various sizes (20, 40, and 90–210 nm) of silver nanoparticles (nAg) blended in a dope solution. To characterize the performance and properties of the prepared membranes, scanning electron microscopy (SEM), water contact angle, protein separation, water flux, [...] Read more.
Polysulfone ultrafiltration membranes were fabricated using various sizes (20, 40, and 90–210 nm) of silver nanoparticles (nAg) blended in a dope solution. To characterize the performance and properties of the prepared membranes, scanning electron microscopy (SEM), water contact angle, protein separation, water flux, and antibacterial tests were conducted. The characterization results revealed that when nAg particles (20 nm) were blended into the base polymer PSF, the PSF/nAg blended membrane had the lowest contact angle (58.5°) and surface energy (110.7 mN/m). When experimenting with ultrafiltration using protein solutions, bare PSF and PSF/nAg-20 blended membranes gave similar values of protein rejection: 93% of bovine serum albumin (BSA) and 70% of lysozyme rejection. Furthermore, SEM studies showed that the surface pore size was reduced by adding 20 nm nAg particles in the casting solution. Most importantly, the introduction of 40 nm nAg particles reduced the growth of bacterial colonies on the membrane surface by up to 72%. These findings revealed that nAg particles are expected to be a potential modifier for the fabrication of an ultrafiltration membrane. Full article
(This article belongs to the Special Issue Frontiers in Nanopore-Based Analytics)
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12 pages, 5636 KiB  
Article
Predicting Finite-Bias Tunneling Current Properties from Zero-Bias Features: The Frontier Orbital Bias Dependence at an Exemplar Case of DNA Nucleotides in a Nanogap
by Ivana Djurišić, Vladimir P. Jovanović, Miloš S. Dražić, Aleksandar Ž. Tomović and Radomir Zikic
Nanomaterials 2021, 11(11), 3021; https://0-doi-org.brum.beds.ac.uk/10.3390/nano11113021 - 10 Nov 2021
Cited by 3 | Viewed by 1622
Abstract
The electrical current properties of single-molecule sensing devices based on electronic (tunneling) transport strongly depend on molecule frontier orbital energy, spatial distribution, and position with respect to the electrodes. Here, we present an analysis of the bias dependence of molecule frontier orbital properties [...] Read more.
The electrical current properties of single-molecule sensing devices based on electronic (tunneling) transport strongly depend on molecule frontier orbital energy, spatial distribution, and position with respect to the electrodes. Here, we present an analysis of the bias dependence of molecule frontier orbital properties at an exemplar case of DNA nucleotides in the gap between H-terminated (3, 3) carbon nanotube (CNT) electrodes and its relation to transversal current rectification. The electronic transport properties of this simple single-molecule device, whose characteristic is the absence of covalent bonding between electrodes and a molecule between them, were obtained using density functional theory and non-equilibrium Green’s functions. As in our previous studies, we could observe two distinct bias dependences of frontier orbital energies: the so-called strong and the weak pinning regimes. We established a procedure, from zero-bias and empty-gap characteristics, to estimate finite-bias electronic tunneling transport properties, i.e., whether the molecular junction would operate in the weak or strong pinning regime. We also discuss the use of the zero-bias approximation to calculate electric current properties at finite bias. The results from this work could have an impact on the design of new single-molecule applications that use tunneling current or rectification applicable in high-sensitivity sensors, protein, or DNA sequencing. Full article
(This article belongs to the Special Issue Frontiers in Nanopore-Based Analytics)
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