ncRNAs in Translational Reprogramming
A special issue of Non-Coding RNA (ISSN 2311-553X).
Deadline for manuscript submissions: closed (30 November 2021) | Viewed by 9754
Special Issue Editors
Interests: tRNA; tRNA fragments; lncRNAs; cardiovascular disease; neurodegeneration; post-transcriptional regulation; RNA-binding proteins (RBPs); translational reprogramming
Interests: microRNAs; lncRNAs; ribonucleoproteins; RNAomics; extracellular RNA; senescence; RNA localization
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Special Issue Information
Dear Colleagues,
Protein synthesis is an energetically expensive cellular process. Its dynamic reprogramming under developmental, environmental, physiological, and pathological cues is essential to various aspects of cell survival and homeostasis. ncRNAs such as miRNAs and long noncoding RNAs being abundantly and ubiquitously expressed in all cell types have emerged as vital players in regulating this final step of the gene-expression pathway. These ncRNAs, through canonical and non-canonical mechanisms, have been shown to reshape the proteome and rewire signaling pathways to optimize gene expression. Further, extensive RNA sequencing and subsequent mechanistic studies are being conducted to discover and elucidate cell- and tissue-specific ncRNAs that affect global or mRNA specific translation. The focus of this Special Issue is on ncRNAs that reprogram mRNA translation. We welcome both original research articles and comprehensive reviews that cover the topic. The interest in their discovery and functional characterization is increasing due to their proposed role in the disease pathogenesis and as novel therapeutic targets.
Dr. Vivek Advani
Dr. Je-Hyun Yoon
Guest Editors
Manuscript Submission Information
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Keywords
- ncRNAs
- miRNA
- long noncoding RNA
- protein synthesis
- mRNA translation
- mRNA localization