Special Issue "Gluten Related Disorders: Coeliac Disease and Beyond"
Deadline for manuscript submissions: closed (31 March 2021).
Interests: coeliac disease; gluten-related disorders; gluten immunogenic peptides and proteins; proteomics; gluten food analysis; immunology; food allergy and intolerance
Interests: coeliac disease; gluten-related disorders; gluten immunogenic peptides and proteins; proteomics; gluten food analysis; immunology; food allergy and intolerance.
Gluten-related disorders (GRDs) have emerged as an epidemiologically relevant phenomenon with an estimated global prevalence of close to 5%. Different mechanisms are involved in the pathogenesis of GRDs. Although they are characterized by peculiar pathogenetic pathways involved in their development, they share similar clinical manifestations making their differential diagnosis challenging.
Among the gluten-related disorders, coeliac disease (CD) is the best known to date. It is characterized by a heterogeneous clinical presentation, affecting any organ or tissue with gastrointestinal, extraintestinal manifestations, subclinical, seronegative, or non-responsive, among others. However, CD research is changing rapidly due to a steady increase in knowledge tackling its pathophysiology, diagnosis, follow-up, and therapeutic options. Indeed, novel findings provide a deeper insight not only of CD, but also of other GRDs: wheat allergy, non-coeliac gluten sensitivity, dermatitis herpetiformis, and gluten ataxia. In this Special Issue, we aim to broaden our knowledge of all essential aspects of GRDs. Potential topics include the following:
- Novel findings providing a deeper insight into the pathogenic mechanisms underlying GRDs.
- Effect of the gluten-free diet (GFD) on GRDs, including patient management after diet instauration, adherence to the diet, and/or ways to monitor it.
- Potential therapeutic strategies based on the immunopathogenesis of these disorders.
- Clinical and pathogenic follow-up of patients with GRDs.
- New knowledge about GFD: technological and nutritional aspects.
Dr. Isabel Comino
Dr. Carolina Sousa
Manuscript Submission Information
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- Gluten-related disorders
- Coeliac disease
- Gluten-free diet
- Clinical manifestations