Special Issue "The Ketogenic Diet for Cancer"

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition and Metabolism".

Deadline for manuscript submissions: 15 February 2022.

Special Issue Editor

Dr. Keisuke Hagihara
E-Mail Website
Guest Editor
Department of Advanced Hybrid Medicine, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan
Interests: ketogenic diet; cancer; frailty; sarcopenia

Special Issue Information

Dear Colleagues,

Currently, the high-fat, low-carbohydrate ketogenic diet is attracting a great deal of attention in the field of cancer treatment. As metabolic alterations, e.g. the Warburg effect, are widespread in various cancer cells, the ketogenic diet is expected to improve the quality of life and prognosis of cancer patients. As Guest Editor of this timely Special Issue, I would like to invite you to contribute your original research articles or reviews on the ketogenic diet for cancer. In several preclinical studies of cancer model mice, the ketogenic diet alongside radiation or chemotherapy is promising. However, the results of early clinical trials of the ketogenic diet are controversial. I would like to discuss the molecular mechanisms of the ketogenic diet for cancer and the comparison with epilepsy therapy in children. I have shown the possibility of the new ketogenic diet regimen for cancer. I also would like to discuss the possibility of early clinical trial/case series and the adequate clinical trial protocol of the ketogenic diet for cancer. For that purpose, I also look forwards to reports on functional foods inducing ketones more efficiently. I invite you to contribute to our understanding of the above topics for this Special Issue relating to the ketogenic diet for cancer.

Dr. Keisuke Hagihara
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • molecular mechanism
  • early clinical trial or case series
  • clinical trial protocol
  • functional food
  • comparison between cancer and epilepsy treatment.

Published Papers

This special issue is now open for submission.
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