Special Issue "Plant-Derived Boosters for the Brain, Gut, and Brain–Gut Axis"

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Phytochemicals and Human Health".

Deadline for manuscript submissions: closed (1 December 2021).

Special Issue Editor

Prof. Dr. Raquel Abalo
E-Mail Website
Guest Editor
Departamento de Ciencias Básicas de la Salud, Facultad de Ciencias de la Salud, Universidad Rey Juan Carlos (URJC), Alcorcón, 28922 Madrid, Spain
Interests: gastrointestinal motility; functional foods; cannabinoids; irritable bowel syndrome; nutraceuticals; enteric nervous system; brain–gut axis
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Without doubt, in the near future, sustainable health will be based on plant-derived food and nutraceuticals. Many components of plants growing on the ground and in water environments are already well recognized for their beneficial health properties, but many are still awaiting identification and functional characterization for their optimal use by the Food and Pharma industries in the development of new efficient and safe functional foods and medicinal products.

The brain–gut axis is increasingly being considered essential for achieving a state of holistic health and well-being. The connection between the brain and the gut involves components from the hormonal, nerve, and immune systems that are recognized to be sensitive to many different influences, among which plant-derived nutraceuticals have attracted attention for their potential preventative and therapeutic role, including that exerted through balancing the gut microbiota. Examples of health application for plant-derived components in this field include functional gastrointestinal disorders (irritable bowel syndrome, functional dyspepsia), organic gastrointestinal pathologies (gastrointestinal cancers, inflammatory bowel diseases, celiac disease, eosinophil-related disorders, other allergies and intolerances) but also systemic (obesity, diabetes, autoimmune), neurodegenerative (Parkinson’s disease, Alzheimer’s disease, prion’s diseases), psychiatric (autism, schizophrenia, depression, anxiety), and infective (Chagas’ disease, COVID-19, salmonellosis, etc.) diseases, as well as iatrogenic disorders (i.e., chemotherapy- or radiotherapy-induced alterations).

Although much has been done, there is clearly still much room for research in this hot field, at the basic, clinical, and epidemiological level. Thus, the many professionals studying the potential benefits of plant-derived nutraceuticals on the brain, the gut, and, especially, brain–gut axis health, are very welcome to contribute to this Special Issue. Studies aimed at clarifying the differential effects of plant-derived nutraceuticals associated with different ages (children, adolescents, elderly), genetic or racial background, physiological conditions (gender, pregnancy, menopause) or other individual circumstances (sport performance, pluripathology, polymedication) are particularly welcome.

We welcome different types of manuscript submissions, including original preclinical and clinical research articles and up-to-date reviews (narrative and systematic reviews, as well as meta-analyses).

Prof. Dr. Raquel Abalo
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Brain–gut axis
  • Functional gastrointestinal disorders
  • Organic gastrointestinal disorders
  • Psychological distress
  • Gastrointestinal infections
  • Antioxidant nutraceuticals
  • Antiinflammatory nutraceuticals
  • Immunomodulatory nutraceuticals
  • Antiproliferative nutraceuticals
  • Enteric nervous system

Published Papers

There is no accepted submissions to this special issue at this moment.
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