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The Right Time to Sleep, the Right Time to Eat: Chronobiology of Metabolism in Health and Disease

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition Methodology & Assessment".

Deadline for manuscript submissions: closed (10 March 2020) | Viewed by 21997

Special Issue Editor


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Guest Editor
1. Institute of Endocrinology and Diabetes, University of Lübeck, D-23538 Lübeck, Germany
2. German Center of Diabetes Research, D-85764 Neuherberg, Germany
Interests: obesity; hypoglycemia; circadian rhythms
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The burden of chronic metabolic disorders, such as obesity and type 2 diabetes, is continuously rising and affects almost all healthcare systems worldwide. In this context, the involvement of chronobiological rhythms in human energy balance is an exciting area of current research. One relevant factor related to physiological energy homeostasis is the timing of meals and sleep. Current evidence supports an important role for the timing of eating and sleeping in the regulation of body weight and metabolism. Furthermore, the interaction between homeostatic/hedonic control of appetite and feeding, physical activity, and sleeping patterns are of highest interest regarding our understanding of human energy homeostasis.

The Special Issue welcomes original and reviews articles highlighting the role of meal and sleep timing and its metabolic consequences for human health with a particular emphasis on chronobiology.

Prof. Dr. Sebastian M. Meyhöfer
Guest Editor

Manuscript Submission Information

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Keywords

  • meal timing
  • food intake
  • metabolic response
  • circadian rhythms
  • sleep/wake timing
  • macronutrient composition

Published Papers (1 paper)

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Review

15 pages, 2588 KiB  
Review
Beneficial Effects of Time-Restricted Eating on Metabolic Diseases: A Systemic Review and Meta-Analysis
by Shinje Moon, Jiseung Kang, Sang Hyun Kim, Hye Soo Chung, Yoon Jung Kim, Jae Myung Yu, Sung Tae Cho, Chang-Myung Oh and Tae Kim
Nutrients 2020, 12(5), 1267; https://0-doi-org.brum.beds.ac.uk/10.3390/nu12051267 - 29 Apr 2020
Cited by 129 | Viewed by 21340
Abstract
Various behavioral and physiological pathways follow a pre-determined, 24 hour cycle known as the circadian rhythm. Metabolic homeostasis is regulated by the circadian rhythm. Time-restricted eating (TRE) is a type of intermittent fasting based on the circadian rhythm. In this study, we aim [...] Read more.
Various behavioral and physiological pathways follow a pre-determined, 24 hour cycle known as the circadian rhythm. Metabolic homeostasis is regulated by the circadian rhythm. Time-restricted eating (TRE) is a type of intermittent fasting based on the circadian rhythm. In this study, we aim to analyze systemically the effects of TRE on body weight, body composition, and other metabolic parameters. We reviewed articles from PubMed, EMBASE, and the Cochrane Library to identify clinical trials that compared TRE to a regular diet. We included 19 studies for meta-analysis. Participants following TRE showed significantly reduced body weight (mean difference (MD), −0.90; 95% confidence interval (CI): −1.71 to −0.10) and fat mass (MD: −1.58, 95% CI: −2.64 to −0.51), while preserving fat-free mass (MD, −0.24; 95% CI: −1.15 to 0.67). TRE also showed beneficial effects on cardiometabolic parameters such as blood pressure (systolic BP, MD, −3.07; 95% CI: −5.76 to −0.37), fasting glucose concentration (MD, −2.96; 95% CI, −5.60 to −0.33), and cholesterol profiles (triglycerides, MD: −11.60, 95% CI: −23.30 to −0.27). In conclusion, TRE is a promising therapeutic strategy for controlling weight and improving metabolic dysfunctions in those who are overweight or obese. Further large-scale clinical trials are needed to confirm these findings and the usefulness of TRE. Full article
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