Recent Development of Resonance-Based Optical Sensors and Biosensors

A special issue of Optics (ISSN 2673-3269). This special issue belongs to the section "Biomedical Optics".

Deadline for manuscript submissions: closed (31 December 2021) | Viewed by 10528

Special Issue Editor

Institute of Applied Physics “Nello Carrara”, CNR-IFAC, Via Madonna del Piano 10, 50019 Sesto Fiorentino, Italy
Interests: bio-photonics and biomedical optics; fiber optics; plasmonics; optical devices; detectors; sensors and sensing
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Special Issue Information

Dear Colleagues,

Resonance-based optical sensors and biosensors have attracted significant research effort due to their unique features compared with their electronic counterparts as well as their potential to provide fast, reliable, real-time detection of physical parameters, chemical compounds, and biomolecules. The integration of these sensors with micro/nanotechnology has provided the opportunity to develop highly sensitive, selective, and repeatable photonic devices and novel sensing/biosensing schemes for use in real-life applications.

This Special Issue “Recent Development of Resonance-Based Optical Sensors and Biosensors” will focus on the unique and novel implementations of optical sensors and biosensors that allow them to perform measurements in challenging physical, chemical, and biomedical applications. We encourage authors to submit original, high quality, relevant research articles and reviews for this Special Issue.

Potential topics include, but are not limited to, recent developments in the following areas:

  • The design/development/optimization of optical sensors;
  • The design/development/optimization of optical biosensors;
  • The design/development/optimization of optical detection platforms;
  • The application of an optical system to measure physical parameters, chemical compounds, or biomolecules
  • The application of an optical system to measure multiple parameters with a single device;
  • Real-time, resonance-based sensing/biosensing;
  • Fiber-optics devices and optical micro-/nano-resonators;
  • Novel photonic devices or methodologies in optical sensing/biosensing

Dr. Francesco Chiavaioli
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Optics is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • resonance-based sensing and biosensing
  • photonic devices
  • optical detection platforms
  • optical biosensors
  • optical resonators
  • fiber gratings

Published Papers (3 papers)

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Editorial

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4 pages, 179 KiB  
Editorial
Recent Development of Resonance-Based Optical Sensors and Biosensors
by Francesco Chiavaioli
Optics 2020, 1(3), 255-258; https://0-doi-org.brum.beds.ac.uk/10.3390/opt1030019 - 28 Nov 2020
Cited by 14 | Viewed by 2522
(This article belongs to the Special Issue Recent Development of Resonance-Based Optical Sensors and Biosensors)

Research

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11 pages, 3181 KiB  
Article
A Miniature pH Probe Using Functional Microfiber Bragg Grating
by Yang Ran, Peng Xiao, Yongkang Zhang, Deming Hu, Zhiyuan Xu, Lili Liang and Bai-Ou Guan
Optics 2020, 1(2), 202-212; https://0-doi-org.brum.beds.ac.uk/10.3390/opt1020016 - 11 Aug 2020
Cited by 11 | Viewed by 2824
Abstract
Operando and precisely probing aqueous pH is fundamentally demanded, both in chemical and biological areas. Conventional pH probes, subjected to the larger size, are probably unfit for application in some extreme scenarios, such as a trace amount of samples. In this paper, we [...] Read more.
Operando and precisely probing aqueous pH is fundamentally demanded, both in chemical and biological areas. Conventional pH probes, subjected to the larger size, are probably unfit for application in some extreme scenarios, such as a trace amount of samples. In this paper, we have further developed the pH sensor that leverages the microfiber Bragg grating with an ultra-compact size down to an order of magnitude of 10−14 m3. Using the electrostatic self-assembly layer-by-layer technique, the functional film consisting of sodium alginate, which harnesses a pH-dependent hygroscopicity, is immobilized on the fiber surface. Consequently, the alteration of aqueous pH could be quantitatively indicated by the wavelength shift of the grating resonance via the refractive index variation of the sensing film due to the water absorption or expulsion. The grating reflections involving fundamental mode and higher order mode exhibit the sensitivities of −72 pm/pH and −265 pm/pH, respectively. In addition, temperature compensation can be facilitated by the recording of the two reflections simultaneously. Furthermore, the modeling and simulation results predict the pivotal parameters of the configuration in sensitivity enhancement. The proposed proof-of-concept enriches the toolbox of pH sensor for catering to the need of detection in some extremely small spaces—for example, the living cells or the bio-tissues. Full article
(This article belongs to the Special Issue Recent Development of Resonance-Based Optical Sensors and Biosensors)
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Review

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30 pages, 3998 KiB  
Review
Optical Fibre Micro/Nano Tips as Fluorescence-Based Sensors and Interrogation Probes
by Simone Berneschi, Andrea Barucci, Francesco Baldini, Franco Cosi, Franco Quercioli, Stefano Pelli, Giancarlo C. Righini, Bruno Tiribilli, Sara Tombelli, Cosimo Trono and Ambra Giannetti
Optics 2020, 1(2), 213-242; https://0-doi-org.brum.beds.ac.uk/10.3390/opt1020017 - 27 Aug 2020
Cited by 10 | Viewed by 4442
Abstract
Optical fibre micro/nano tips (OFTs), defined here as tapered fibres with a waist diameter ranging from a few microns to tens of nanometres and different tip angles (i.e., from tens of degrees to fractions of degrees), represent extremely versatile tools that have attracted [...] Read more.
Optical fibre micro/nano tips (OFTs), defined here as tapered fibres with a waist diameter ranging from a few microns to tens of nanometres and different tip angles (i.e., from tens of degrees to fractions of degrees), represent extremely versatile tools that have attracted growing interest during these last decades in many areas of photonics. The field of applications can range from physical and chemical/biochemical sensing—also at the intracellular levels—to the development of near-field probes for microscope imaging (i.e., scanning near-field optical microscopy (SNOM)) and optical interrogation systems, up to optical devices for trapping and manipulating microparticles (i.e., optical tweezers). All these applications rely on the ability to fabricate OFTs, tailoring some of their features according to the requirements determined by the specific application. In this review, starting from a short overview of the main fabrication methods used for the realisation of these optical micro/nano structures, the focus will be concentrated on some of their intriguing applications such as the development of label-based chemical/biochemical sensors and the implementation of SNOM probes for interrogating optical devices, including whispering gallery mode microcavities. Full article
(This article belongs to the Special Issue Recent Development of Resonance-Based Optical Sensors and Biosensors)
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