Special Issue "Advances in Drug and Drug-Conjugate Design for Improved Pharmacokinetics and Targeting"
Deadline for manuscript submissions: 1 December 2021.
Interests: molecular imaging and therapy; fluorescence-guided surgery; in vivo biodistribution; nanobody; tracer design
Special Issues and Collections in MDPI journals
Targeting moieties that specifically interact with molecules expressed or involved in pathophysiological conditions are increasingly being exploited in precision medicine for diagnostic and therapeutic purposes. Targeted drugs and drug-conjugates based on antibodies, peptides, or small molecules can significantly improve treatment efficacy, while unwanted side-effects are reduced. Analogously, molecular targeted contrast agents are gaining in popularity for patient stratification as companion diagnostics or for image-guided surgery.
Nevertheless, careful considerations on all aspects of drug and drug-conjugate design (e.g., type of targeting vehicle, size, and physicochemical properties of all components; linking or loading strategy, binding characteristics, or selected target) are key to assuring a proper pharmacokinetic profile complying with the intended application. This Special Issue focuses on the latest findings and advances in targeted drug and drug-conjugate design resulting in improved pharmacokinetics and eventually in better therapeutic and diagnostics applications.
Prof. Dr. Sophie Hernot
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceuticals is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- targeted imaging and therapy
- in vivo biodistribution
- improved pharmacokinetics
- drug design
- targeted drugs
- drug conjugates