Special Issue "Applications of Medicinal Bioinorganic Chemistry"
Deadline for manuscript submissions: 29 April 2022.
Interests: analytical chemistry; bioinorganic chemistry; chelation therapy
Interests: bioinorganic chemistry; nucleic acids; molecular recognition; multicomponent pharmaceutical materials; co-drugs
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In this Special Issue of Pharmaceuticals entitled “Applications of Medicinal Bioinorganic Chemistry”, we aim to explore the potential of bioinorganic chemistry applied to medicinal chemistry. The growing field of bioinorganic chemistry has expanded the knowledge of the functions of metal ions in the human organism, their homeostatic control, and the influence of disequilibrium on the onset and progression of different pathologies.
The therapeutic use of metal-based drugs dates back to the starting of civilization. A number of metal-based drugs can be found in the pharmacopoeia at the start of the last century, such as mercuric ions in the treatment of syphilis; silver as one of the few drugs capable of healing infections, burns, and wounds, and preventing contagious diseases; gold in the treatment of rheumatoid arthritis; or lithium as an antidepressant.
Nowadays, the use of metal ions in the diagnosis and treatment of diseases is continuously increasing, finding applications as contrast agents for CT and MRI, in developing essential diagnosis techniques in modern medicine, and as drugs for clinical use in anticancer therapy. The knowledge of the molecular base of neurodegenerative diseases (Parkinson’s, Alzheimer’s, etc.) has opened the way to new drugs for the treatment of these burdensome diseases. In medicinal chemistry, chelating agents have been used for the scavenging of toxic metal ions, in particular iron chelators for thalassemia patients, which extended both life expectance and quality of life.
In this Special Issue, Pharmaceuticals welcomes original research articles and reviews devoted to life science, pharmaceutical science, and clinical science research within the field of applications of medicinal bioinorganic chemistry.
Prof. Dr. Guido Crisponi
Dr. Alicia Dominguez-Martin
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceuticals is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Metal-based drugs
- Contrast agents
- Anticancer drugs
- Neurodegenerative diseases
- Chelating agents