Remotely Controlled Nanomedicines for Precision Medicine

Dear Colleagues,

Nanomedicinal formulations that can be remotely controlled to target and elicit their therapeutic payload constitute a promising approach towards more potent personalized therapies. These systems comprise nanocarriers that can respond to external stimuli such as heat, light, ultrasound and magnetic fields. In their simplest form, they are synthesized by an encapsulating material, for example, a responsive polymer (i.e., a block copolymer) or a lipid that is specifically designed to carry molecular cargo (i.e., drug molecules, nucleic acids, proteins, etc.) and to respond to stimuli cues. Alternatively, organic components are combined with inorganics (i.e., metallic nanoparticles, quantum dots, magnetic nanoparticles, etc.) to form more elaborate hybrid ensembles with extreme precision capabilities and high therapeutic indexes. RCNs can be used in combinational therapies to deliver multiple drug molecules and also to combine delivery events with adjuvant therapeutic modalities (i.e., hyperthermia, photodynamic therapy, ablation, etc.) in a spatiotemporally controlled manner that maximizes therapeutic efficiency without compromising healthy tissue. This Special Issue focuses on the most recent advances in RCN concepts and technologies for precision medicine.

Dr. George Pasparakis
Guest Editor

Manuscript Submission Information

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• Remotely controlled drug delivery systems
• Stimuli-responsive nanomaterials
• Targeted therapeutics
• Precision nanomedicines
• Nanocarriers
• Nanoparticles