Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
5.4
4.5
Journals
Plants
Special Issues
Antioxidant Capacity of Plant Extracts
share announcement

Antioxidant Capacity of Plant Extracts

A special issue of Plants (ISSN 2223-7747). This special issue belongs to the section "Phytochemistry".

Deadline for manuscript submissions: closed (31 October 2022) | Viewed by 18628

Special Issue Editors

Dr. Mariangela Marrelli

E-Mail Website
Guest Editor
Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, CS, Italy
Interests: medicinal plants; plant extracts; natural bioactive compounds; essential oils; nutraceuticals; antioxidant activity; antiproliferative activity; anti-inflammatory properties; photocytotoxic compounds
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Filomena Conforti

E-Mail Website
Guest Editor
Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, I-87036 Rende (CS), Italy
Interests: phytochemical compounds; ethnopharmacology; alimurgic plants; biological activity of natural compounds; phytocosmetics
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Giancarlo Statti

E-Mail Website
Guest Editor
Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende (CS), Italy
Interests: medicinal plants; plant extracts; natural bioactive compounds; essential oils; nutraceuticals; antioxidant activity; antiproliferative activity; anti-inflammatory properties; photocytotoxic compounds

Special Issue Information

Dear Colleagues,

The involvement of oxidative stress in the pathogenesis of different diseases is well known, and the beneficial effects of botanicals and diet-sourced antioxidants on human health have attracted much attention in recent decades. In addition to the role of endogenous antioxidants, exogenous compounds such as phenolic acids, flavonoids, and tocopherols contained in foodstuffs, food supplements, and pharmaceuticals are extremely important to counteract the effects of reactive oxygen species.

To this end, non-conventional “green” extraction techniques, characterized by high extraction efficiency and efficacy, aim to impart selectivity and optimize the sensitivity of utilized methodology, thus allowing to obtain an increased concentration of antioxidant compounds in plant extracts. Furthermore, the identification of even better performant analytical methods for the assessment of the antioxidant capacity of botanicals is currently being pursued.

We would like to cordially invite you to participate in this Special Issue by submitting research articles, reviews, or short communications concerning the extraction, isolation, and structural determination of antioxidant secondary metabolites and the in vitro or in vivo evaluation of their potential beneficial effects on human health. We look forward to your contributions.

Dr. Mariangela Marrelli
Prof. Dr. Filomena Conforti
Prof. Dr. Giancarlo Statti
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Plants is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • phenolic compounds
  • flavonoids
  • oxidative stress
  • plant secondary metabolites
  • botanicals
  • nutraceuticals

Published Papers (6 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

14 pages, 1273 KiB  
Article
Phytochemical Composition and Antioxidant and Anti-Inflammatory Activities of Ligularia fischeri Turcz: A Comparison between Leaf and Root Extracts
by Tae-Hyu Kim, Van-Long Truong and Woo-Sik Jeong
Plants 2022, 11(21), 3005; https://0-doi-org.brum.beds.ac.uk/10.3390/plants11213005 - 07 Nov 2022
Cited by 3 | Viewed by 1765
Abstract
Ligularia fischeri Turcz leaves are widely consumed and have multiple health benefits. We aimed to evaluate the differences in the phytochemical composition and biological properties of the root and leaf extracts from L. fischeri. The root extract exhibited higher antioxidant capacity and [...] Read more.
Ligularia fischeri Turcz leaves are widely consumed and have multiple health benefits. We aimed to evaluate the differences in the phytochemical composition and biological properties of the root and leaf extracts from L. fischeri. The root extract exhibited higher antioxidant capacity and total flavonoid levels than the leaf extract. GC/MS analysis revealed the presence of various volatiles, diterpenoids, sesquiterpenes, and other non-polar compounds. Moreover, these extracts enhanced cellular antioxidant defense by reducing the level of reactive oxygen species and upregulating the expression of catalase and heme oxygenase-1 in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells. The root and leaf extracts also exerted anti-inflammatory effects by suppressing nitric oxide production and diminishing the levels of inducible nitric oxide synthase, cyclooxygenase-2, and interleukin-1β in LPS-stimulated macrophages. Overall, these findings suggest that L. fischeri root extract contains diverse bioactive compounds for the development of nutraceuticals or functional foods with antioxidant and anti-inflammatory activity. Full article
(This article belongs to the Special Issue Antioxidant Capacity of Plant Extracts)
►▼ Show Figures

Figure 1

14 pages, 1538 KiB  
Article
Effect of Germination and Illumination on Melatonin and Its Metabolites, Phenolic Content, and Antioxidant Activity in Mung Bean Sprouts
by Pimolwan Siriparu, Panyada Panyatip, Thanawat Pota, Juthamat Ratha, Chawalit Yongram, Tarapong Srisongkram, Bunleu Sungthong and Ploenthip Puthongking
Plants 2022, 11(21), 2990; https://0-doi-org.brum.beds.ac.uk/10.3390/plants11212990 - 06 Nov 2022
Cited by 8 | Viewed by 6440
Abstract
Mung bean (Vigna radiata L.) sprouts are increasingly consumed and have become part of a healthy diet. The sprouts are composed of proteins, carbohydrates, and biochemical compounds. During germination, the phytochemical compounds are significantly elevated, especially under stress conditions such as salinity, [...] Read more.
Mung bean (Vigna radiata L.) sprouts are increasingly consumed and have become part of a healthy diet. The sprouts are composed of proteins, carbohydrates, and biochemical compounds. During germination, the phytochemical compounds are significantly elevated, especially under stress conditions such as salinity, drought, extreme temperature, and illumination. The present study examined the effects of light and germination time on the bioactive compounds in mung bean sprout extracts. Mung bean seeds were sprouted under different light exposure conditions, and the phytochemical composition and antioxidant activity of sprout extracts were determined compared to seeds. The results show that tryptophan sharply decreased during germination. On the contrary, melatonin, polyphenols, and total phenolic content (TPC) were elevated with increased germination time, correlated with increased antioxidant activity. Sprouts germinated in the dark presented higher levels of melatonin and TPC compared with those germinated under 12 h light exposure (3.6- and 1.5-fold, respectively). In conclusion, germination can enhance valuable phytochemicals and antioxidant activity of mung bean sprouts. Mung bean sprouts may be a good alternative functional food for promoting human health. Full article
(This article belongs to the Special Issue Antioxidant Capacity of Plant Extracts)
►▼ Show Figures

Figure 1

16 pages, 1689 KiB  
Article
Development of an Effective Sonotrode Based Extraction Technique for the Recovery of Phenolic Compounds with Antioxidant Activities in Cherimoya Leaves
by Beatriz Martín-García, María José Aznar-Ramos, Vito Verardo and Ana María Gómez-Caravaca
Plants 2022, 11(15), 2034; https://0-doi-org.brum.beds.ac.uk/10.3390/plants11152034 - 04 Aug 2022
Cited by 4 | Viewed by 1170
Abstract
The leaves of Annona cherimola Mill (cherimoya) are a potential source of phenolic compounds that have been shown to have beneficial properties. Therefore, this study focuses on establishing an ultrasonic-assisted extraction of phenolic compounds in cherimoya leaves using a sonotrode. For that purpose, [...] Read more.
The leaves of Annona cherimola Mill (cherimoya) are a potential source of phenolic compounds that have been shown to have beneficial properties. Therefore, this study focuses on establishing an ultrasonic-assisted extraction of phenolic compounds in cherimoya leaves using a sonotrode. For that purpose, a Box-Behnken design based on a response surface methodology (RSM) was used to optimize factors, such as amplitude, extraction time and solvent composition to obtain the maximum content of phenolic compounds by HPLC-MS and the maximum in-vitro antioxidant activity by DPPH, ABTS and FRAP assays in ‘Fino de Jete’ cherimoya leaves. The optimal conditions were 70% amplitude, 10 min and 40:60 ethanol/water (EtOH/H2O) (v/v). The results obtained under these optimum conditions by using a sonotrode were compared with those from an ultrasonic bath; briefly, recovery of phenolic compounds by sonotrode was 2.3 times higher than a bath. Therefore, these optimal conditions were applied to different varieties ‘Campas’, ‘Fino de Jete’ and ‘Negrito Joven’ harvested in the Tropical Coast of Granada (Spain). A total of 39 phenolic compounds were determined in these cherimoya leaf extracts, 24 phenolic compounds by HPLC-MS and 15 proanthocianidins by HPLC-FLD. 5-p-coumaroylquinic acid, lathyroside-7-O-α-l-rhamnopyranoside and quercetin hexose acetate were first identified in cherimoya leaves. The most concentrated phenolic compounds were the flavonoids, such as rutin and quercetin hexoside and proanthocyanidins including monomers. Almost no significant differences in the phenolic content in these cultivars were found (11–13 mg/g d.w. for phenolic compounds and 11–20 mg/g d.w. for proanthocyanidins). In addition, sonotrode ultrasonic-assisted extraction has been shown to be an efficient extraction technique in the phenolic recovery from cherimoya leaves that could be implemented on an industrial scale. Full article
(This article belongs to the Special Issue Antioxidant Capacity of Plant Extracts)
►▼ Show Figures

Figure 1

14 pages, 659 KiB  
Article
Effects of Maturity and Thermal Treatment on Phenolic Profiles and In Vitro Health-Related Properties of Sacha Inchi Leaves
by Suwapat Kittibunchakul, Chatrapa Hudthagosol, Promluck Sanporkha, Suwimol Sapwarobol, Uthaiwan Suttisansanee and Yuraporn Sahasakul
Plants 2022, 11(11), 1515; https://0-doi-org.brum.beds.ac.uk/10.3390/plants11111515 - 05 Jun 2022
Cited by 10 | Viewed by 2627
Abstract
Sacha inchi (Plukenetia volubilis L.) has been adopted as a novel economic crop with well-studied nutritional and bioactive benefits for human health. Sacha inchi seeds and oil have high commercial value but scant research has focused on its leaves. This study investigated [...] Read more.
Sacha inchi (Plukenetia volubilis L.) has been adopted as a novel economic crop with well-studied nutritional and bioactive benefits for human health. Sacha inchi seeds and oil have high commercial value but scant research has focused on its leaves. This study investigated and compared phenolic compositions, antioxidant potentials and in vitro health-related properties of both young and mature sacha inchi leaves after freeze-drying and oven-drying processes. Results showed that p-coumaric acid, 4-hydroxybenzoic acid, ferulic acid and gallic acid were predominantly detected in both young and mature leaves that also exhibited similar total phenolic contents (TPCs), while higher TPCs were detected in freeze-dried than in oven-dried leaves. Mature leaves exhibited higher antioxidant potential than young leaves after freeze-drying, while the opposite results were observed for oven-drying. Overall in vitro health-related activities were higher in mature leaves compared to young leaves regardless of the drying process. Knowledge gained from this study can be used to encourage prospective utilization of sacha inchi leaves as a source of health-promoting compounds. This, in turn, will increase the commercial value of the leaves and provide a wider market variety of sacha inchi products. Full article
(This article belongs to the Special Issue Antioxidant Capacity of Plant Extracts)
►▼ Show Figures

Figure 1

19 pages, 3883 KiB  
Article
In Vitro Anti-Photoaging and Skin Protective Effects of Licania macrocarpa Cuatrec Methanol Extract
by Kon Kuk Shin, Sang Hee Park, Hye Yeon Lim, Laura Rojas Lorza, Nurinanda Prisky Qomaladewia, Long You, Nur Aziz, Soo Ah Kim, Jong Sub Lee, Eui Su Choung, Jin Kyung Noh, Dong-Keun Yie, Deok Jeong, Jongsung Lee and Jae Youl Cho
Plants 2022, 11(10), 1383; https://0-doi-org.brum.beds.ac.uk/10.3390/plants11101383 - 23 May 2022
Cited by 7 | Viewed by 2745
Abstract
The Licania genus has been used in the treatment of dysentery, diabetes, inflammation, and diarrhea in South America. Of these plants, the strong anti-inflammatory activity of Licania macrocarpa Cuatrec (Chrysobalanaceae) has been reported previously. However, the beneficial activities of this plant on skin [...] Read more.
The Licania genus has been used in the treatment of dysentery, diabetes, inflammation, and diarrhea in South America. Of these plants, the strong anti-inflammatory activity of Licania macrocarpa Cuatrec (Chrysobalanaceae) has been reported previously. However, the beneficial activities of this plant on skin health have remained unclear. This study explores the protective activity of a methanol extract (50–100 μg/mL) in the aerial parts of L. macrocarpa Cuatrec (Lm-ME) and its mechanism, in terms of its moisturizing/hydration factors, skin wrinkles, UV radiation-induced cell damage, and radical generation (using RT/real-time PCR, carbazole assays, flowcytometry, DPPH/ABTS, and immunoblotting analysis). The anti-pigmentation role of Lm-ME was also tested by measuring levels of melanin, melanogenesis-related genes, and pigmentation-regulatory proteins. Lm-ME decreased UVB-irradiated death in HaCaT cells by suppressing apoptosis and inhibited matrix metalloproteinases 1/2 (MMP1/2) expression by enhancing the activity of extracellular signal-regulated kinase (ERK), c-Jun N-terminal kinase (JNK), and p38. It was confirmed that Lm-ME displayed strong antioxidative activity. Lm-ME upregulated the expression of hyaluronan synthases-2/3 (HAS-2/3) and transglutaminase-1 (TGM-1), as well as secreted levels of hyaluronic acid (HA) via p38 and JNK activation. This extract also significantly inhibited the production of hyaluronidase (Hyal)-1, -2, and -4. Lm-ME reduced the melanin expression of microphthalmia-associated transcription factor (MITF), tyrosinase, and tyrosinase-related protein-1/2 (TYRP-1/2) in α-melanocyte-stimulating hormone (α-MSH)-treated B16F10 cells via the reduction of cAMP response element-binding protein (CREB) and p38 activation. These results suggest that Lm-ME plays a role in skin protection through antioxidative, moisturizing, cytoprotective, and skin-lightening properties, and may become a new and promising cosmetic product beneficial for the skin. Full article
(This article belongs to the Special Issue Antioxidant Capacity of Plant Extracts)
►▼ Show Figures

Figure 1

13 pages, 1379 KiB  
Article
Boosted Antioxidant Effect Using a Combinatory Approach with Essential Oils from Origanum compactum, Origanum majorana, Thymus serpyllum, Mentha spicata, Myrtus communis, and Artemisia herba-alba: Mixture Design Optimization
by Wessal Ouedrhiri, Hamza Mechchate, Sandrine Moja, Ramzi A. Mothana, Omar M. Noman, Andriy Grafov and Hassane Greche
Plants 2021, 10(12), 2817; https://0-doi-org.brum.beds.ac.uk/10.3390/plants10122817 - 20 Dec 2021
Cited by 3 | Viewed by 2677
Abstract
Several studies have demonstrated the possible synergistic effect as an effective strategy to boost the bioactivity of essential oils. Using this framework, this study was conducted to effectively establish the ideal combination of six essential oils from different plants (Origanum compactum, [...] Read more.
Several studies have demonstrated the possible synergistic effect as an effective strategy to boost the bioactivity of essential oils. Using this framework, this study was conducted to effectively establish the ideal combination of six essential oils from different plants (Origanum compactum, Origanum majorana, Thymus serpyllum, Mentha spicata, Myrtus communis, and Artemisia herba-alba) that would express the best antioxidant activity. Each mixture was optimized using a mixture design approach to generate the most effective blend. The 2,2-diphenyl-1-picrylhydrazyl radical scavenging method was used as a reference method to assess the antioxidant activity. Each essential oil’s composition was identified using the GC/MS method. The single essential oil activities demonstrated variable antioxidant effects, and following the mixture design approach, the optimal antioxidant blend was revealed, as two mixtures demonstrated the best antiradical activity with 79.46% obtained with the mixture of O. majorana (28%) and M. spicata (71%) and 78.8% obtained with the mixture O. compactum (64%), O. majorana (13%), and T. serpyllum (21%). This study proposes a practical way to elaborate mixtures in the search for a boosting effect that can be oriented for the food or pharmaceutical industry. Full article
(This article belongs to the Special Issue Antioxidant Capacity of Plant Extracts)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-6
Back to TopTop