Wood- and Plant-Based Nanocellulose: Applications in the Biomedical Field

A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Polymer Applications".

Deadline for manuscript submissions: closed (5 October 2022) | Viewed by 3115

Special Issue Editors


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Guest Editor
Materials Research Institute, Athlone Institute of Technology, Athlone, Co. Westmeath, Ireland
Interests: hydrogel; biopolymers; drug delivery; tissue engineering; polymer characterisation

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Guest Editor
Forestry Technology and Engineering Department, Universidade Federal do Paraná (UFPR), Curitiba, Paraná, Brazil
Interests: nanocellulose; fast-pyrolysis bio-oil; biocomposites; biorefinery; nanotechnology; plasma treatment

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Guest Editor
Embrapa Florestas, Colombo, Paraná, Brazil
Interests: nanocellulose; functionalisation; biocomposites; cold plasma technology

Special Issue Information

Dear Colleagues,

Nanocellulose derived from wood and plants has been suggested to be used for various applications due to their inherited properties. However, in the field of biomaterials, they are required to be further processed to improve their biocompatibility. This is a requirement not easily attainable by vegetable nanocellulose, due to the ordered nature of its chains and the various components within its structure, such as hemicellulose and lignin. Additionally, despite being a bioinert material, there are no enzymes in the human body that degrade this material in vivo. Therefore, this Special Issue is launched to cover recent techniques and synthesis of plant nanocellulose for biomedical applications. Original papers and reviews on, but not restricted to, the following topics are welcomed:

  • Blending nanocellulose with biocompatible materials for tissue engineering;
  • Functionalisation of nanocellulose for targeted drug delivery;
  • Nanocellulose scaffolds for orthopaedic implants

Dr. Gabriel G. De Lima
Dr. Pedro Henrique Gonzalez De Cademartori
Dr. Washington Luiz Esteves Magalhães
Guest Editors

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Keywords

  • natural fibres
  • scaffolds
  • tissue engineering
  • cytocompatibility
  • controlled release
  • drug delivery
  • biomass
  • biomedical applications

Published Papers (1 paper)

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Research

20 pages, 3113 KiB  
Article
Characterization of Gels and Films Produced from Pinhão Seed Coat Nanocellulose as a Potential Use for Wound Healing Dressings and Screening of Its Compounds towards Antitumour Effects
by Tielidy A. de M. de Lima, Gabriel Goetten de Lima, Bor Shin Chee, Jeferson G. Henn, Yvonne J. Cortese, Mailson Matos, Cristiane V. Helm, Washington L. E. Magalhães and Michael J. D. Nugent
Polymers 2022, 14(14), 2776; https://0-doi-org.brum.beds.ac.uk/10.3390/polym14142776 - 07 Jul 2022
Cited by 4 | Viewed by 2369
Abstract
The reuse of agro-industrial waste assumes great importance today. Pinhão is the seed of Araucaria angustifolia, which is native to the mountains of southern Brazil, Paraguay, and Argentina. The coat is a by-product of this seed and is rich in phenolic compounds. [...] Read more.
The reuse of agro-industrial waste assumes great importance today. Pinhão is the seed of Araucaria angustifolia, which is native to the mountains of southern Brazil, Paraguay, and Argentina. The coat is a by-product of this seed and is rich in phenolic compounds. The present study aimed to use the residue as a precursor material for the production of nanocellulose through the mechanical defibrillation process and perform the characterization of the films and the gel to investigate the effect on the physical and regenerative properties when incorporated with polyvinyl alcohol (PVA). The modulus of elasticity was higher when the MFC of pinhão was added to the PVA. Film and gel had their cytotoxicity tested by MTT assay using 3T3 fibroblast and Schwann cancer cells, and a migration assay was also performed using the scratch test on HaCat keratinocyte cells. For the scratch test, film and gel samples with low concentration presented a complete scratch closure in 72 h. Molecular docking was performed and quercetin had the ideal interaction score values, so it was used with the PACAP protein which presented a slightly moderate interaction with the protein synthesis of Schwann cells, presenting compactness of the compound after 14 ns. Full article
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