Special Issue "State of the Art of Seaweeds and Their Bioactive Extracts: Extraction and Applications"

A special issue of Processes (ISSN 2227-9717). This special issue belongs to the section "Biological Processes and Systems".

Deadline for manuscript submissions: closed (31 May 2021).

Special Issue Editors

Dr. Cristina Soares
E-Mail Website
Guest Editor
REQUIMTE–LAQV, Instituto Superior de Engenharia do Porto, Instituto Politécnico do Porto, R. Dr. António Bernardino de Almeida 431, 4249-015 Porto, Portugal
Interests: bioresources; seaweeds; food safety and processing; functional products; bioactivities; green technologies
Special Issues, Collections and Topics in MDPI journals
Dr. Clara Grosso
E-Mail Website
Guest Editor
REQUIMTE–LAQV, Instituto Superior de Engenharia do Porto, Instituto Politécnico do Porto, R. Dr. António Bernardino de Almeida 431, 4249-015 Porto, Portugal
Interests: seaweeds; medicinal plants; secondary metabolites; bioactivities; green extraction processes; nanotechnology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Macroalgae are an attractive raw material due to their low cost, abundance, composition of added-value compounds, and the possibility of their cultivation in aquaculture. Marine macroalgae represent a rich source of bioactive compounds with several applications, especially in the food, cosmetics, and medical fields. Among their added-value compounds, polyphenols, polysaccharides, carotenoids, proteins, and fatty acids have been increasingly explored due to their beneficial effects on human health, such as antimicrobial, antioxidant, antidiabetic, cardioprotective, and neuroprotective effects. Moreover, to follow the principles of green chemistry, green extraction processes have also been developed in recent years to obtain bioactive extracts from macroalgae. Besides the beneficial effects of seaweeds on human health, these natural sources of bioactive compounds can also accumulate undesirable toxic elements with potential health risks. For this reason, the performance of adequate extraction and purification techniques of extracts from seaweeds may mitigate the amount of excessive toxic components, ensuring healthy and safe products for commercialization. Besides, other limitations, such as low stability and bioavailability, chemical degradation during storage, and sensitivity to ultraviolet light and oxygen, need to be overcome, using, for example, nanoencapsulation techniques in order to achieve superior biological activities of the extracts.

This Special Issue will gather recent advances in seaweed extracts and their application in numerous fields. It aims to focus on understanding the application of seaweed extracts and the associated potential health effects.

We invite researchers to contribute original research articles and reviews on several pertinent topics, including but not limited to:

  • Extraction techniques;
  • Isolation and quantification of bioactive compounds;
  • Identification of target compounds in the extracts;
  • Biological activities;
  • Toxicity assessment;
  • Analytical techniques to quantify and identify bioactive compounds;
  • Sensorial impact;
  • Organoleptic, nutritional, and health characteristics of final products;
  • Development and application of new food, nutraceutical, and cosmeceutical products;
  • Stability and bioavailability;
  • Scaling up to industrial levels;
  • Biorefinery approach.

Dr. Cristina Soares
Dr. Clara Grosso
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Processes is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • seaweeds
  • conventional extraction methods
  • advanced extraction techniques
  • biological activities
  • application
  • isolation and purification techniques
  • identification and quantification methods
  • bioavailability

Published Papers (1 paper)

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Research

Article
Multi-Step Subcritical Water Extracts of Fucus vesiculosus L. and Codium tomentosum Stackhouse: Composition, Health-Benefits and Safety
Processes 2021, 9(5), 893; https://0-doi-org.brum.beds.ac.uk/10.3390/pr9050893 - 19 May 2021
Viewed by 889
Abstract
Mental health and active aging are two of the main concerns in the 21st century. To search for new neuroprotective compounds, extracts of Codium tomentosum Stackhouse and Fucus vesiculosus L. were obtained through multi-step (four step) subcritical water extraction using a temperature gradient. [...] Read more.
Mental health and active aging are two of the main concerns in the 21st century. To search for new neuroprotective compounds, extracts of Codium tomentosum Stackhouse and Fucus vesiculosus L. were obtained through multi-step (four step) subcritical water extraction using a temperature gradient. The safety assessment of the extracts was performed by screening pharmaceutical compounds and pesticides by UHPLC-MS/MS, and iodine and arsenic levels by ICP-MS. Although the extracts were free of pharmaceutical compounds and pesticides, the presence of arsenic and high iodine contents were found in the first two extraction steps. Thus, the health-benefits were only evaluated for the fractions obtained in steps 3 and 4 from the extraction process. These fractions were tested against five brain enzymes implicated in Alzheimer’s, Parkinson’s, and major depression etiology as well as against reactive oxygen and nitrogen species, having been observed a strong enzyme inhibition and radical scavenging activities for the step 4 fractions from both seaweed species. Regarding the variation of the chemical composition during the extraction, step 1 fractions were the richest in phenolic compounds. With the increase in temperature, Maillard reaction, caramelization and thermo-oxidation occurred, and the resulting products positively affected the antioxidant capacity and the neuroprotective effects. Full article
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