Dear Colleagues,

Developing new biophysical tools opens gateways for us to observe, quantify, model, and manipulate processes in biological systems, ranging from molecules and proteins to cells, organs, multicellular organisms or even the whole ecosystem. To do so, we draw expertise and techniques from a plethora of different disciplines, such as biochmistry, bioinformatics, neuroscience, sensorics or statistical physics. This Special Issue on “Developing Biophysical Tools” will bring the most recent advances of in silico, in vitro, and in vivo methods to a broad audience, with a focus on three main aspects: Firstly, understanding which biological questions might be adressed with novel tools; secondly, new ideas on how to enhance traditional methods or develop entirely new ones; and thirdly, how to combine methods and tools from different disciplines. The latter point is particularly important to gain a holistic insight into the complex world of biological interactions.

Topics include but are not limited to:

• Developing methods and analyses of molecular dynamics simulations;
• Spatiotemporal modeling and simulations;
• Statistical physics applied to experimental phenomena (transport, phase changes etc.);
• Multicorrelative, experimental approaches (microscopy + AFM, microscopy + microcfluidics, etc.);
• Novel sensor designs (tension, pH, Voltage);
• Acquiring dynamic information from static structural information.

Dr. Kristyna Pluhackova
Dr. Gotthold Fläschner
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Processes is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• method development
• (biological) processes
• biophysical tools
• (atomic force) microscopy
• theoretical models
• molecular dynamics simulations
• cryoEM
• spectroscopy
• mass spectrometry
• sensors