Special Issue "Microbial Communities in Health and Disease"
Deadline for manuscript submissions: closed (29 February 2020).
Interests: molecular systems biotechnology, specifically on using integrated experimental and modeling approaches for investigating problems in human health and medicine; systems biology of cytokine signaling in inflammatory diseases; inter-kingdom signaling interactions between bacteria and human cells in GI tract infections; the development of microfluidic model systems for combinatorial drug screening and vascular tissue engineering
Interests: metabolic engineering; tissue engineering; systems biology
Special Issues, Collections and Topics in MDPI journals
The role of the microbiome in human health and disease is becoming increasingly important. Seminal studies have identified changes in the composition of the microbiota, as well in its functional output, in the context several diseases, including obesity and diabetes, cancer, autism, and inflammatory disorders. Advances in next-generation sequencing technologies for characterizing the composition of microbial communities and in metabolomic methods for identifying metabolites produced by the community have been instrumental in these advances; however, while correlational associations have been made, causal relationships between specific members of the microbial community and specific diseases are poorly understood. Systems biology tools and quantitative approaches can help better understand the role of the microbiota in maintaining homeostasis in their animal host as well as in the initiation and propagation of disease.
This Special Issue on “Microbial Communities in Health and Disease” seeks contributions on quantitative and experimental aspects of microbiome research. Topics of interest include, but are not limited to, the following:
- Models for quantitative analysis of microbial communities associated with their animal host
- A simulation of microbial communities in animal hosts using genome-scale modeling
- Microbial community structure (composition)–function (metabolite output) relationships
- Multi-omic data integration for describing microbial community function
- Novel model-systems and tools for controlled studies of microbe–microbe and microbe–host interactions
- Temporal and spatial dynamics of microbiota in animal hosts
In addition, a small number of critical reviews on molecular mechanisms mediating microbiome effects in the host are also invited.
Prof. Dr. Arul Jayaraman
Prof. Dr. Kyongbum Lee
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Processes is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- microbiota composition
- community dynamics
- temporal heterogeneity
- spatial dynamics