Dear Colleagues,

It is well known that osseointegration is viewed as a mode of implant anchorage that simulates a simple wound healing phenomenon. Today, we have evidence that osseointegration is, in fact, a foreign body reaction that involves the immunologically derived bony demarcation of an implant to shield it from nearby tissues. Marginal bone resorption around an oral implant cannot be properly understood without realizing the foreign body nature of the implant itself. Whereas the immunological response may be positive, resulting in implant longevity, adverse immunological reactions may cause marginal bone loss in combination with combined factors. The role of bacteria in the process of marginal bone loss is smaller than previously believed due to combined defense mechanisms of inflammation and immunological reactions; however, if such defense fails, then we may see bacterially induced marginal bone loss as well.

In this Special Issue, we want to provide a global overview of the advances in oral surgery and oral medicine ranging from new advances in oral surgery techniques to the molecular etiological aspects of oral and periodontal disease pathogenesis. This Special Issue will also cover new advances in preclinical pharmacological therapeutic strategies of oral diseases, including studies on pharmacological drugs used in the dental field.

On behalf of the journal Prosthesis, you are cordially invited to contribute an article to the Special Issue “Osseointegration of Oral implants: Importance of Bone Implant Interface and Periodontal Health in Long-Term Survival Rates”. Research articles and reviews are welcome. Case reports will also be considered for publication.

Prof. Dr. Roya Zandparsa
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Prosthesis is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• oral surgery
• oral implants
• periodontal disease
• biomaterials
• oral rehabilitation
• oral disease–systemic disease
• peri-implantitis
• sinus lift
• antibiotics