Special Issue "Case Reports of Autoimmune Diseases"
A special issue of Reports (ISSN 2571-841X).
Deadline for manuscript submissions: 31 December 2022.
2. Epigenética del Cáncer y Nanomedicina, Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Hospital Universitario Central de Asturias, Avda. Hospital Universitario s/n, 33011 Oviedo, Spain
Interests: autoimmunity; T1D; cancer; epigenetics; aging
Special Issues, Collections and Topics in MDPI journals
The immune system has two complementary functions. The most intuitive known function is to identify foreign or abnormal elements in the organism to which it belongs, such as bacteria, viruses, and tumor cells, and control and eliminate them—this is habitually called the immune response. Another obvious but much less represented function of the immune system, however, is that it must identify healthy structures belonging to the said organism and respect them—this is known as immunological tolerance. This narrow field where the immune system should operate is located between two frontiers: the inability to respond adequately to nosological threats, which would imply a certain degree of immunodeficiency, and the inability to respect its own healthy structures, which would imply the processes of autoimmunity.
Up to 10% of the population has a diagnosis of an autoimmune disease, and such diseases are a common cause of medical consultation. Scientific advances and new therapeutic approaches (cancer immunotherapy, new immunosuppressants) and diagnostic tests (nuclear medicine imaging, radiometabolic studies, molecular biology, and genetics studies) have renewed interest in these diseases in the medical field. Their variability of clinical expression both by the structures that may be affected (connective tissue, skin, nervous system, endocrine, digestive, hematological) as well as the abnormal activation of different arms of the immune system and the degree of intensity of the underlying inflammation make each patient a particular case to study and learn about, and case reports are adequate tools to define specific characteristics of these diseases.
For this Special Issue, we are inviting manuscripts in “Case report” format with clinical interest related to this topic that shall allow further advancements in our knowledge of autoimmunity. We are particularly interested in pathophysiological studies, but diagnostic or therapeutic approaches will also be welcome.
Dr. Juan Luis Fernandez-Morera
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- immune response
- autoimmune diseases