Alcohol-Induced Liver Injury

Dear Colleagues,

Chronic alcohol abuse is a significant cause of cirrhosis and liver failure in adults worldwide. Alcoholic liver disease (ALD) is a pathological process characterized by progressive liver damage that leads to steatosis, steatohepatitis, fibrosis, and finally cirrhosis. Eventually, cirrhosis may progress to hepatic decompensation and hepatocellular cancer. Therefore, ALD is an important cause of morbidity and mortality. There is an urgent need to develop efficient strategies for patients with ALD.

Although remarkable achievements has been made in the mechanisms of ALD, there is still no effective therapy for ALD. Recently, there has been growing studies in elucidating the role of foods and food components as suppressors of alcohol–induced oxidative stress and liver damage.

This Special Issue would like to deepen the relationship between food components and preventive effect for ALD. The studies using in vitro and/or in vivo models are welcome.

Prof. Dr. Akiko Kojima-Yuasa
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• alcoholic liver disease
• hepatitis
• liver fibrosis
• food components
• hepatocyte
• hepatic stellate cells
• reactive oxygen species
• alcohol dehydrogenase
• cytochrome P450 2E1