Special Issue "Cyanobacterial Toxins: Genotoxic and Cytotoxic Activity, Molecular Targets and Chemical Interactions"
Deadline for manuscript submissions: 28 February 2022.
Interests: cyanobacterial toxins; genetic toxicology; in vitro; advanced 3D cell models; toxicogenomics; ecotoxicology; combined exposures
Cyanobacteria are becoming a global environmental and human health problem as cyanobacterial blooms are increasing in frequency and magnitude worldwide, due to progressive eutrophication of water bodies and climate change. They produce a wide range of bioactive compounds including highly toxic cyanotoxins. Concern about their potential adverse effects, particularly after chronic exposure to low doses has been raised as humans can be exposed to cyanotoxins over a significant portion of their life span, with children being at higher risk for illnesses development. The mechanisms behind the toxic effects of cyanotoxins differ according to their chemical structure and molecular targets. In order to set the appropriate safety measures for the protection of human and animal health, as well as the environment throughout, toxicological evaluation of the emerging cyanotoxins (e.g., microcystins, cylindrospermopsin, nodularins, microginins, BMAA, etc.) is urgently needed. This Special Issue will highlight research on the cellular and molecular mechanisms behind the geno/toxic activity of cyanotoxins in the form of pure compounds and complex mixtures of several cyanotoxins. Moreover, papers describing novel predictive biomarkers of cyanotoxin geno/toxic effects identified by traditional toxicological approaches correlated to ‘omics‘ data are welcome.
Dr. Bojana Žegura
Dr. Alja Štern
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxins is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Emerging cyanotoxins
- mechanisms of action
- combined effects
- risk assessment
- molecular structure