Special Issue "Mycotoxins and Their Chromatographic-Based Detection Technology"

A special issue of Toxins (ISSN 2072-6651). This special issue belongs to the section "Mycotoxins".

Deadline for manuscript submissions: 31 December 2021.

Special Issue Editors

Dr. Siegrid De Baere
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Guest Editor
Department of Pharmacology, Toxicology and Biochemistry, Ghent University, 9820 Merelbeke, Belgium
Interests: research related to the mycotoxin problem in livestock; method development for quantification of mycotoxins and metabolites in animal matrices using LC-MS/MS and LC-HRMS; investigation of toxicity, toxicokinetics, and residues of (emerging) mycotoxins in livestock; interactions between mycotoxins and pathogens in livestock and models for in vitro and in vivo safety and efficacy testing of mycotoxin detoxifiers
Prof. Dr. Siska Croubels
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Guest Editor
Department of Pharmacology, Toxicology and Biochemistry, Ghent University, 9820 Merelbeke, Belgium
Interests: mycotoxins; toxicokinetics; toxicity; binders; modifiers; in vitro; in vivo; food production animals; porcine biomedical model for humans; bioanalysis; biomarkers; cytochrome P450; ABC transporters; impact on infectious diseases; veterinary drugs; pharmacokinetics; pharmacodynamics; PK/PD modeling; residues; food safety; bioanalysis
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Special Issue Information

The worldwide contamination of crops and subsequently of food and feed with mycotoxins is of major agro-economic importance. In addition, these mycotoxins can have a negative impact on human and animal health.

The identification and quantification of mycotoxins in these commodities, as well as the biomonitoring in biological matrices, is of key importance both in mycotoxin monitoring and exposure assessment. Analytical techniques play a major role in the analysis of mycotoxins and their metabolites. However, the development of new analytical methods is often challenging, certainly when a multianalyte determination is required, for the following reasons : (1) the different chemical properties of various classes of mycotoxins, (2) the lack of commercial availability of analytical standards of some mycotoxins or metabolites, thus complicating method development and toxin quantification, (3) the presence of modified metabolites, (4) the complexity of the matrices to be analyzed, and (5) the low amounts detected.

Today, technical platforms based on chromatographic techniques (mainly liquid chromatography (LC) and gas chromatography (GC)) and combined with spectrometric detection (ultraviolet, fluorescence, mass spectrometry) are widely used tools for the identification and quantification of these analytes and being the techniques of choice when a multianalyte determination is required. Recently, the use of high-resolution mass spectrometry (HRMS) has allowed the identification of novel mycotoxins and metabolites and boosted the advances in metabolomics studies.

This Special Issue is dedicated to the development, validation, and application of novel methods based on chromatographic separation (single or multidimensional LC, GC, CE) in combination with spectrometric detection techniques for the identification and quantification of major and emerging mycotoxins in different matrices (crops, food, feed, biological matrices). In addition, novel sampling techniques (e.g., microsampling, such as dried blood spots (DBS), volumetric absorptive microsampling (VAMS), etc.), as well as innovative and high-throughput sample preparation and purification methods are welcome.

Dr. Siegrid De Baere
Prof. Dr. Siska Croubels
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxins is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • mycotoxins
  • metabolites
  • identification
  • quantification
  • chromatography
  • multimethods
  • mass spectrometry
  • sample preparation
  • method development
  • validation

Published Papers

This special issue is now open for submission.
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