Special Issue "Methicillin-Resistant Staphylococci and Macrococci at the Interface of Human and Animal Health"
Deadline for manuscript submissions: closed (30 September 2020).
The global importance of methicillin-resistant Staphylococcus aureus (MRSA) strains on human and animal health continues, even considering decreasing MRSA rates in some parts of the world. Subsequent to the emergence of hospital- and community-associated MRSA, livestock-associated MRSA and MSSA of different clonal lineages became an additional threat for human and animal health contributing significantly to morbidity, mortality and socio-economic costs.
However, many aspects of their genetic basis, origin, distribution, transmission, virulence profile and introduction into the health care systems are still poorly understood. The enormous diversity of the SCCmec as mobile genetic element harboring the methicillin resistance-encoding genes and other genes mediating resistances towards antibiotics, heavy metals and metalloids reflects the flexibility of staphylococci and their relatives, the macrococci, to resist the selection pressures occurring in their environment. The recent expansion of the mec “alphabet” by the detection of the mecC, mecB and mecD genes as well as the identification of plasmid-borne methicillin resistance in macrococci and staphylococci is additionally challenging the routine diagnostics as well as epidemiological studies. Moreover, the impact of coagulase-negative staphylococci and coagulase-positive non-S. aureus species as well as the role of macrococci as source for methicillin resistance-encoding genetic elements in S. aureus are only scantily investigated. Also widely unknown is the impact of virulence factors, in particular toxins, on the adaptation of Staphylococcaceae members to novel hosts and/or ecosystems.
Focusing on toxins and methicillin resistance in staphylococci and macrococci, this special issue aims to characterize basic, epidemiological, ecological and medical aspects on the interface between animal keeping, wildlife and putative other niches on one hand and the human and animal health on the other. In particular, submissions, which specifically address the One World – One Health concept in this field, are welcome.
Prof. Dr. Karsten Becker
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxins is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Methicillin resistance
- Oxacillin resistance
- Betalactam resistance
- One Health