Special Issue "Research on Biotoxins Based on Model Organisms"
A special issue of Toxins (ISSN 2072-6651).
Deadline for manuscript submissions: 31 January 2022.
Interests: cyanobacteria; toxins; bioactive compounds; zebrafish embryo model; natural products
Special Issues and Collections in MDPI journals
Special Issue in Marine Drugs: Algal Toxins
Special Issue in Toxins: Cyanotoxins
Special Issue in Toxins: Toxic Non-Proteinogenic Amino Acids (NPAA)
Special Issue in Marine Drugs: Algal Toxins II, 2017
Systems-level approaches lie at the forefront of the toxicology, including our understanding of biotoxins. Such approaches are driven by the integration of classical toxicological techniques with state-of-the-art technologies (e.g., omics, in vivo visualization) in relation to the increasing complexity from biochemical, molecular, and cellular to organismal, and even population, levels. More importantly, however, systems-level toxicology has been specifically enabled by the availability of an ever-growing number of model organisms as toxicological systems, which are able to effectively target both relevant “levels” of toxicity (i.e., molecular, cellular, organismal and population) and in the context of naturally occurring biotoxins potentially provide direct relevance to plant and animal health (e.g., agriculture, veterinary medicine, aquaculture/fisheries) and ecosystems (i.e., ecotoxicology). Indeed, studies over the past half-century have seen “evolution” from bacterial and other microbial (e.g., yeast) models to a myriad of invertebrate animal (e.g., Drosphila, C. elegans, Artemia salina) and plant models (e.g., Arabidopsis, Chlamydomonas) to non-mammalian vertebrate systems (e.g., Xenopus, Zebrafish). Evolution of these model systems in relation to toxicology has, in turn, progressed hand in hand with advances in the basic science (in the same systems) of genomes and molecular biology, development, physiology, immunology, and numerous other areas that have further potentiated their utility as toxicological models.
This Special Issue invites both reviews and original research contributions related to the topic of model organisms, and the application of toxicological methodologies to these systems, toward advancement of our understanding of biotoxins from microbes, plants, and animals in relation to (1) their targets, mechanisms, and modes of action; (2) their fate including uptake, bioavailability, and metabolism; and (3) their larger relevance in areas of both human and animal health, as well as agriculture (e.g., crop plants) and ecotoxicology.
Prof. Dr. John Berry
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxins is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- model organisms
- microbial toxins
- plant toxins
- systems biology
- in vivo techniques