Infant Botulism and Adult Intestinal Botulism

A special issue of Toxins (ISSN 2072-6651). This special issue belongs to the section "Bacterial Toxins".

Deadline for manuscript submissions: closed (31 December 2022) | Viewed by 4006

Special Issue Editor

Department of Bacteriology, Graduate School of Medical Sciences, Kanazawa University, Kanazawa 920-8640, Japan
Interests: Clostridium botulinum; botulinum toxin; clostridial neurotoxins
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

A rare but life-threatening disease, botulism is caused by botulinum neurotoxins produced by Clostridium botulinum and other neurotoxigenic clostridia. Multiple clinical forms of this pathology are recognized. Colonization in the lumen of the intestine by these clostridia and subsequent production of the toxins in the intestine lead to intestinal toxemia botulism. This is called infant botulism when it occurs in infants younger than 1 year of age, and adult intestinal botulism when it occurs in adults and children over1 year of age.

The aim of this Special Issue of Toxins is to provide an overview of the current knowledge on infant and adult intestinal botulism. Reviews, original articles, and short communications about the etiology, epidemiology, clinical manifestations, diagnosis, therapy of infant and adult intestinal botulism are all welcome.

Prof. Dr. Yukako Fujinaga
Guest Editor

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Keywords

  • Infant botulism
  • adult intestinal botulism
  • intestinal toxemia botulism
  • botulinum neurotoxin

Published Papers (1 paper)

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Research

11 pages, 883 KiB  
Article
Infant Botulism: Checklist for Timely Clinical Diagnosis and New Possible Risk Factors Originated from a Case Report and Literature Review
by Robertino Dilena, Mattia Pozzato, Lucia Baselli, Giovanna Chidini, Sergio Barbieri, Concetta Scalfaro, Guido Finazzi, Davide Lonati, Carlo Alessandro Locatelli, Alberto Cappellari and Fabrizio Anniballi
Toxins 2021, 13(12), 860; https://0-doi-org.brum.beds.ac.uk/10.3390/toxins13120860 - 02 Dec 2021
Cited by 3 | Viewed by 3423
Abstract
Infant botulism is a rare and underdiagnosed disease caused by BoNT-producing clostridia that can temporarily colonize the intestinal lumen of infants less than one year of age. The diagnosis may be challenging because of its rareness, especially in patients showing atypical presentations or [...] Read more.
Infant botulism is a rare and underdiagnosed disease caused by BoNT-producing clostridia that can temporarily colonize the intestinal lumen of infants less than one year of age. The diagnosis may be challenging because of its rareness, especially in patients showing atypical presentations or concomitant coinfections. In this paper, we report the first infant botulism case associated with Cytomegalovirus coinfection and transient hypogammaglobulinemia and discuss the meaning of these associations in terms of risk factors. Intending to help physicians perform the diagnosis, we also propose a practical clinical and diagnostic criteria checklist based on the revision of the literature. Full article
(This article belongs to the Special Issue Infant Botulism and Adult Intestinal Botulism)
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