Special Issue "Pseudomonas aeruginosa Toxins and Disease"

A special issue of Toxins (ISSN 2072-6651). This special issue belongs to the section "Bacterial Toxins".

Deadline for manuscript submissions: closed (30 September 2021).

Special Issue Editor

Assoc. Prof. Brant Wagener
Guest Editor
Department of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA
Interests: trauma; secondary bacterial infections; amyloids; cognitive dysfunction; chronic critical illness; GPCR trafficking/signaling

Special Issue Information

Pseudomonas aeruginosa is a common cause of nosocomial pneumonia (among other sites of infection) in intensive care units and immunocompromised individuals. A recent working group indicated that pneumonia is not only a localized, acute disease, but can cause non-pulmonary end-organ dysfunction that leads to deleterious long-term health consequences for patients. Interestingly, many of these effects are mediated by the virulent toxins and avoidance methods possessed by the bacterium. These methods include, but are not limited to, the type III secretion system, flagellin, mucin production, and quorum sensing. Although we know much about how these toxins function, there is still much to learn about how the bacterium uses these methods to cause infection and disease.

This Special Issue will focus on how Pseudomonas aeruginosa can lead to virulent infection, maintain a balance between colonization and infection, lead to short- and long-term end-organ dysfunction, and how its virulent toxins and avoidance methods play a role in these processes.

Assoc. Prof. Brant Wagener
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxins is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • toxins
  • Pseudomonas aeruginosa
  • Type III secretion system
  • cystic fibrosis
  • pneumonia
  • end-organ dysfunction
  • quorum sensing
  • virulence factors
  • mucus

Published Papers

There is no accepted submissions to this special issue at this moment.
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