Selected Papers from the 2017 Venoms to Drugs Conference

A special issue of Toxins (ISSN 2072-6651). This special issue belongs to the section "Animal Venoms".

Deadline for manuscript submissions: closed (28 February 2018) | Viewed by 13546

Special Issue Editor

Special Issue Information

Dear Colleagues,

The 2017 Venoms to Drugs meeting will be held at the Peppers Noosa Resort, Queensland, 9–14 October, 2017. The conference will focus on venom from cone snails, scorpions, spiders, snakes, and other species continue to provide an immense reservoir of potent bioactive peptides that target specific enzymes, ion channels, and receptors. As such, they represent major sources of lead compounds for both the development of pharmacological tools and novel drugs. This Special Issue aims to bring together active scholars and researchers to present their current scholarly work in venoms to drugs.

For additional links to the conference that you may find useful, please visit the following link: http://venomstodrugs.com/welcome-venoms-drugs

Prof. Dr. Bryan Grieg Fry
Guest Editor

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers (1 paper)

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Review

15 pages, 2935 KiB  
Review
Sea Anemones: Quiet Achievers in the Field of Peptide Toxins
by Peter J. Prentis, Ana Pavasovic and Raymond S. Norton
Toxins 2018, 10(1), 36; https://0-doi-org.brum.beds.ac.uk/10.3390/toxins10010036 - 08 Jan 2018
Cited by 83 | Viewed by 12696
Abstract
Sea anemones have been understudied as a source of peptide and protein toxins, with relatively few examined as a source of new pharmacological tools or therapeutic leads. This is surprising given the success of some anemone peptides that have been tested, such as [...] Read more.
Sea anemones have been understudied as a source of peptide and protein toxins, with relatively few examined as a source of new pharmacological tools or therapeutic leads. This is surprising given the success of some anemone peptides that have been tested, such as the potassium channel blocker from Stichodactyla helianthus known as ShK. An analogue of this peptide, ShK-186, which is now known as dalazatide, has successfully completed Phase 1 clinical trials and is about to enter Phase 2 trials for the treatment of autoimmune diseases. One of the impediments to the exploitation of sea anemone toxins in the pharmaceutical industry has been the difficulty associated with their high-throughput discovery and isolation. Recent developments in multiple ‘omic’ technologies, including genomics, transcriptomics and proteomics, coupled with advanced bioinformatics, have opened the way for large-scale discovery of novel sea anemone toxins from a range of species. Many of these toxins will be useful pharmacological tools and some will hopefully prove to be valuable therapeutic leads. Full article
(This article belongs to the Special Issue Selected Papers from the 2017 Venoms to Drugs Conference)
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