Dear Colleagues,

The goal of cancer immunotherapy is to induce regression of solid and hematological malignancies, indirectly attacking the cancer by regulating the patient’s immunity, establishing perduring antitumour memory and limiting adverse reactions. Although cancer immunotherapy is a rapidly evolving field which has provided significant improvements for cancer patients, tumour-induced immunosuppression and immunoresistance to treatment pose significant challenges. Combining conventional methods for cancer treatment such as surgery, chemotherapy and radiation therapy with improved immunotherapy approaches might overcome tumour resistance and enhance clinical efficacy. Similarly, the success of vaccine-based immunotherapy might be reinforced by other cutting-edge approaches such as immune checkpoint inhibitor, adoptive cell transfer and engineered T-cell therapy.

In this Special Issue, we want to deliberate on how to improve therapeutic cancer immunotherapies by discussing the potential problems and solutions for overcoming tumour resistance and enhancing clinical efficacy. Similarly, we would like to take advantage of novel knowledge and technologies, in order to reach the next breakthrough in cancer immunotherapy.

We warmly welcome all scientists working in these fields to submit their manuscripts to our Special Issue.

We look forward to receiving your contributions.

Dr. Lionel Poulin
Prof. Dr. Damya Laoui
Guest Editors

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• cancer vaccines
• tumor antigens
• suppression mechanism
• immunotherapy
• dendritic cell vaccines