Cancer Microenvironment in Veterinary Oncology and Therapeutic Opportunities
A special issue of Veterinary Sciences (ISSN 2306-7381). This special issue belongs to the section "Veterinary Microbiology, Parasitology and Immunology".
Deadline for manuscript submissions: closed (31 July 2021) | Viewed by 734
Special Issue Editors
Interests: Small animal oncology; opthalmology and neurology
2. Animal Science and Study Centre (CECA), Food and Agrarian Sciences and Technologies Institute (ICETA), P. Gomes Teixeira, Apartado 55142, 4051-401 Porto, Portugal
Interests: veterinary clinical oncology; oncobiology and therapy
Special Issue Information
Dear Colleagues,
For several decades, cancer studies have mainly focused on the genetic instability of tumour cells, somehow neglecting the direct impact of the microenvironment in cancer evolution, often relegated to the role of “mutation trigger”. Nowadays, it is common knowledge that solid tumours are not simple clumps of similar cancer cells, but rather “abnormal organs” composed of multiple cell phenotypes embedded in modified extracellular matrices, forming the so-called “tumour microenvironment”. In one single tumour mass, it is possible to find mesenchymal supporting cells (fibroblasts and adipocytes), endothelial cells and cells of the immune system (macrophages and lymphocytes), to name the most common ones. The genomic and epigenomic abnormalities of cancer cells trigger microenvironment changes that lead to the formation of a supportive “tumour microenvironment” that favours neoplastic cell proliferation, survival, differentiation, and spread. The aim of this Special Issue is to publish original research work or reviews on the topic of the microenvironment role in animal cancer development as well as therapeutic strategies targeting these tumour–microenvironment interactions.
Prof. Dr. Augusto J.F. Matos
Dr. Andreia Santos
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Veterinary Sciences is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- veterinary oncology
- tumour microenvironment
- targeting therapy
