Special Issue "New Frontiers in Small DNA Virus Research"

A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "General Virology".

Deadline for manuscript submissions: 30 June 2022.

Special Issue Editors

Dr. Katerina Strati
E-Mail Website
Guest Editor
Department of Biological Sciences, University of Cyprus, 1678 Nicosia, Cyprus
Interests: oncogenic viruses; papillomaviruses; virus-cell interactions; mouse models of infection and viral disease
Dr. Dohun Pyeon
E-Mail Website
Guest Editor
Department of Microbiology and Molecular Genetics, Michigan State University, 567 Wilson Rd. BPS 4197, East Lansing, MI 48824-4320, USA
Interests: human papillomaviruses (HPV); tumor virology; virus-host interactions; antiviral immunity; antitumor immunity; immunotherapy

Special Issue Information

Dear Colleagues,

Although new technologies have significantly advanced our understanding of viruses and their interactions with host and environment in recent decades, we are continuously facing new challenges. The COVID-19 pandemic has shown us that our accumulated knowledge and experience become instrumental to cope with the urgent necessities of vaccine development. Nevertheless, the enormous casualties in one year of the pandemic has awoken us to the fact that we are far from well-prepared for future threats compounding current unsolved problems caused by viruses.

Studies in small DNA viruses including polyomavirus, papillomavirus, and adenovirus have led us to the breakthroughs of modern molecular and cellular biology and advanced our understanding of virally-mediated diseases (cancers, autoimmunity, etc.). For example, SV40 research opened the door to discoveries of basic molecular (transcriptional regulation) and oncogenic (tumor suppressors and tyrosine kinases) mechanisms. In addition, while the HPV and HBV research brought us the two most successful cancer vaccines, adenovirus is being used as one of the most popular viral vectors in gene therapies and vaccines, including the COVID-19 vaccines.

To continue our success and usher a new chapter in small DNA virus research, we would like to invite you to share your recent findings or perspectives on big questions and future directions, including but not limited to: viral oncogenesis, commensalism and pathogenesis, host immunity, host cell stemness, epigenetic dysregulation, noncoding RNAs,  metabolism, viral vectors, and new experimental models.

Dr. Katerina Strati
Dr. Dohun Pyeon
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Papillomavirus
  • HPV
  • polyomavirus
  • cervical cancer
  • head and neck cancer
  • oral cancer
  • skin cancer
  • anal cancer
  • innate immunity
  • immune evasion
  • immunotherapy
  • noncoding RNA
  • circular RNA
  • metabolism
  • small DNA virus
  • commensalism
  • virome
  • tumor virus
  • carcinogenesis
  • oncogenesis
  • frontier
  • chromatin
  • epigenetics
  • stem cell
  • virus entry
  • cancer vaccine
  • persistent infection
  • experimental model
  • new technology
  • AdV; adenovirus
  • polyomavirus
  • mMuPV1
  • HBV
  • polyomavirus
  • JC virus
  • BK virus
  • viral vectors
  • Merkel cell polyoma virus

Published Papers

This special issue is now open for submission.
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