Special Issue "Genomics of Giant Viruses"
Deadline for manuscript submissions: 31 December 2021.
Interests: hepatitis viruses; HIV; epidemiological surveillance of infections; emerging viruses; genomics of giant viruses; interactions of plant viruses with humans
Interests: giant viruses; large viruses; evolution; host–virus interactions
Special Issues and Collections in MDPI journals
The giant viruses discovered in 2003 have since been shown to be common in our biosphere. Their genetic diversity has expanded considerably, and sequences closest to those of giant viruses are frequently and sometimes abundantly found in metagenomes, potentially leading to the assembly of complete genomes. However, some isolated giant viruses have a genome sufficiently divergent to escape such detections based on similarity searches. This suggests that knowledge on the diversity of giant viruses is still rather incomplete. Analyses of the genomes of giant viruses revealed a complexity similar to that of small cellular organisms, with characteristics that distinguish them from classical viruses, including genes that are hallmarks of cellular organisms. In addition, they demonstrate the significant mosaicism of these genomes resulting from numerous transfers of sequences and integration events as well as considerable proportions of ORFans. These various features make the genomics of giant viruses, that we are addressing in this Special Issue, a hot topic in the field of evolutionary biology.
Prof. Philippe Colson
Prof. Dr. Jônatas Abrahão
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- giant virus
- lateral sequence transfers