Optical Coherence Tomography: An Emerging Technology for Biomedical Imaging and Optical Biopsy

A special issue of Vision (ISSN 2411-5150).

Deadline for manuscript submissions: closed (30 April 2021) | Viewed by 3505

Special Issue Editor

Department of Ophthalmology, Creteil Hospital, Paris Est University, Créteil, France
Interests: retinal imaging; age-related macular degeneration; retinal dystrophies; big data; artificial intelligence
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The extraordinary advancements in OCT technology from Huang’s and Fujimoto’s first description in the 90s allow today a histology-like anatomical description of the retina. The progressive increase in the resolution and speed of the OCT instruments has lead to a paradigm shift in the clinical management and evaluation of macular diseases.

This special issue is aimed at highlighting the recent developments of OCT and OCT-derived techniques, along with the role of high-resolution OCT in macular disease, from the valuable biomarkers of disease progression to the insights on macular disease pathogenesis.

Contributions include a broad scope of research, for instance, recent technological developments, novel OCT-derived techniques, and fundamental and clinical studies.

Dr. Alexandra Miere
Guest Editor

Manuscript Submission Information

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Keywords

  • OCT
  • imaging
  • retina

Published Papers (1 paper)

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Research

11 pages, 6120 KiB  
Article
Progression from Type 2 Macular Neovascularization to Fibrovascular Pigment Epithelial Detachment
by Hoang Mai LE, Gérard Mimoun, Salomon Y. Cohen, Camille Jung, Oudy Semoun and Eric H. Souied
Vision 2021, 5(2), 16; https://0-doi-org.brum.beds.ac.uk/10.3390/vision5020016 - 25 Mar 2021
Cited by 1 | Viewed by 3006
Abstract
The aim of this study was to report unusual progression of type 2 macular neovascularization (MNV) associated with age-related macular degeneration (AMD), high myopia or angioid streaks. Retrospective multicentric observational case series data were used. Eyes that progressed from type 2 MNV secondary [...] Read more.
The aim of this study was to report unusual progression of type 2 macular neovascularization (MNV) associated with age-related macular degeneration (AMD), high myopia or angioid streaks. Retrospective multicentric observational case series data were used. Eyes that progressed from type 2 MNV secondary to AMD, high myopia or angioid streaks to fibrovascular pigment epithelial detachment (PED) were included. A total of 29 treatment-naive eyes from 29 patients with type 2 MNV secondary to AMD (n = 14), high myopia (n = 10) or angioid streaks (n = 5) that progressed to a fibrovascular PED on Spectral Domain-Optical Coherence Tomography were used. This progression occurred within 3 months after anti-VEGF therapy initiation. Logarithm of minimum angle of resolution (LogMAR) visual acuity improved significantly after anti-VEGF therapy, from 0.55 (SD ± 0.30) (20/63–20/80) at baseline to 0.30 (20/40) at 3 months, and 0.33 (20/40) at the final follow-up (mean follow up: 3.68 years). Mean number of intravitreal injections per year for patients with a total follow-up ≥ 12 months (n = 24) was 4.3 ± 2.1 per year. Progression from type 2 MNV to a fibrovascular PED may occur in patients suffering from AMD, high myopia or angioid streaks. This progression appears early after initiation of anti-VEGF therapy and is associated with a favorable visual and anatomical outcome, at least on a short follow up basis. Full article
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