X-ray Structure Determination of Naphthalen-2-yl 1-(Benzamido(diethoxyphosphoryl)methyl)-1H-1,2,3-triazole-4-carboxylate
, Rachid Ouarsal 1, Anouar Alami 1,*, Mohamed El Omari 3, Abderrazzak Assani 4, Mohamed Saadi 4 and Lahcen El Ammari 4Round 1
Reviewer 1 Report
This 'Short Note' by Serigne Abdou Khadir Fall et al. describes the structural determination by single-crystal X-ray diffraction of the title compound, "naphthalen-2-yl (S)-1-(benzamido(diethoxyphosphoryl)methyl)-1H-1,2,3-triazole-4-carboxylate". The synthesis and characterization - besides the crystal structure - have been previously published by the authors in Molbank, 2021, M1285. But the structure has apparently also been published (or is pending) as a CSD Communication (DOI: 10.5517/ccdc.csd.cc29ygg6)?
Furthermore, the title compound is termed the (S)-enantiomer, however, the space group is the centro-symmetric P21/c, so both enantiomers are present in the crystal structure.
Author Response
Dear reviewer
All the Authors thank you for your efforts and comments aimed to improve the quality of our manuscript.
Please find attached the revised version of our manuscript. You will find below the answer to your comments and suggestions, point by point.
Best regards
Prof. Anouar Alami
The synthesis and characterization - besides the crystal structure - have been previously published by the authors in Molbank, 2021, M1285. But the structure has apparently also been published (or is pending) as a CSD Communication (DOI: 10.5517/ccdc.csd.cc29ygg6)?
The communication in CSD regarding this article DOI: 10.5517/ccdc.csd.cc29ygg6 has been removed as shown in the attached message.
Furthermore, the title compound is termed the (S)-enantiomer, however, the space group is the centro-symmetric P21/c, so both enantiomers are present in the crystal structure.
Since the title compound crystallizes in the space group P21/c which is centro-symmetrical, then we remove the absolute configuration (S) in all of the text.
Author Response File: 
Author Response.pdf
Reviewer 2 Report
Manuscript ID: molbank-1625092
Type of manuscript: Short Note
Title: Naphthalen-2-yl (S)-1-(benzamido(diethoxyphosphoryl)methyl)-1H-1,2,3-triazole-4-carboxylate: Single-Crystal X-ray Structure Determination
Authors: Serigne Abdou Khadir Fall, Sara Hajib, Younas Aouine, Rachid Oursal, Anouar Alami, Mohamed El Omari, Abderrazzak Assani, Mohamed Saadi, Lahcen El Ammari
In this Short Note, the authors determined the crystal structure of naphthalen-2-yl (S) -1- (benzamido (diethoxy-22-phosphoryl) methyl) -1H-1,2,3-triazole-4-carboxylate by a single-crystal X-ray diffraction.
The manuscript is well written and well organized. The results are clearly presented and discussed. I suggest publishing the manuscript after a minor correction. Namely, the authors stated that the title compound was resynthesized in excellent yield and high regioselectivity. I wonder what the yield of the compound was now relative to the yield obtained in reference 14? It would be good to comment on that in this manuscript.
Author Response
Dear reviewer
All the Authors thank you for your efforts and comments aimed to improve the quality of our manuscript.
Please find attached the revised version of our manuscript. You will find below the answer to your comments and suggestions
Best regards
Prof. Anouar Alami
I wonder what the yield of the compound was now relative to the yield obtained in reference 14? It would be good to comment on that in this manuscript.
The title compound was resynthesized with an excellent yield of about 95%
Author Response File: Author Response.pdf
Round 2
Reviewer 1 Report
The authors have now updated the manuscript accordingly.
