Impact of hemodialysis dose and frequency on survival of patients on chronic hemodialysis in Lithuania during 1998–2005
Material and methods. We analyzed data of all patients who started hemodialysis due to endstage renal disease in Lithuania between January 1, 1998, and December 31, 2005. The information about hemodialysis frequency, duration, and adequacy (according to Kt/V) was obtained from medical documentation. The overall survival rate was estimated using the Kaplan- Meier method. Survival comparisons were made using the log-rank or Breslow tests. Univariate Cox proportional hazards analysis was used to select variables significantly associated with the risk of death; then these variables were included in multivariate Cox proportional hazards models.
Results. During the study period, from 2428 patients who started chronic hemodialysis, 58.5% of patients started hemodialysis three times a week. More than one-third (36.2%) of patients were dialyzed twice weekly, and 5.3% of patients started hemodialysis once weekly. Survival analysis revealed that patients dialyzed less than three times per week survived shorter than patients receiving a higher dialysis dose. Duration of HD session of ≤8 hours per week was an independent risk factor for mortality. A higher mean Kt/V was associated with better survival of patients on chronic hemodialysis.
Conclusions. Dialysis frequency and weekly duration of HD sessions were dependent on HD accessibility in Lithuania during the period of 1998–2005. Better survival of patients on chronic hemodialysis was associated with a higher hemodialysis dose.
Stankuvienė, A.; Žiginskienė, E.; Kuzminskis, V.; Bumblytė, I.A. Impact of hemodialysis dose and frequency on survival of patients on chronic hemodialysis in Lithuania during 1998–2005. Medicina 2010, 46, 516. https://0-doi-org.brum.beds.ac.uk/10.3390/medicina46080074
Stankuvienė A, Žiginskienė E, Kuzminskis V, Bumblytė IA. Impact of hemodialysis dose and frequency on survival of patients on chronic hemodialysis in Lithuania during 1998–2005. Medicina. 2010; 46(8):516. https://0-doi-org.brum.beds.ac.uk/10.3390/medicina46080074Chicago/Turabian Style
Stankuvienė, Asta, Edita Žiginskienė, Vytautas Kuzminskis, and Inga A. Bumblytė 2010. "Impact of hemodialysis dose and frequency on survival of patients on chronic hemodialysis in Lithuania during 1998–2005" Medicina 46, no. 8: 516. https://0-doi-org.brum.beds.ac.uk/10.3390/medicina46080074