Automated Motion Analysis of Bony Joint Structures from Dynamic Computer Tomography Images: A Multi-Atlas Approach
Abstract
:1. Introduction
2. Materials and Methods
2.1. Subject Recruitment
2.2. CT Acquisitions
2.3. Atlas Dataset
2.4. Multi-Atlas Segmentation
2.5. Dynamic Registration Framework
2.6. Landmark Propagation and Kinematic Parameters Estimation
2.7. Validation
2.8. Statistical Analysis
3. Results
3.1. Multi-Atlas Segmentation
3.2. Dynamic Registration
3.3. Landmark Propagation
3.4. Kinematic Parameters
3.5. Discussion
3.6. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Dynamic Acquisition | Static Acquisitions | |
---|---|---|
Knee | ||
Tube Voltage | 80 kV | 120 kV |
Tube current | 50 mA | 80 mA |
Tube rotation time | 0.28 s | 0.28 s |
Reconstructed slice thickness | 2.5 mm | 2.5 mm |
Field of View | 500 mm | 500 mm |
Collimation | 256 × 0.625 mm | 256 × 0.625 mm |
Dose length product | 107.91 mGycm | 23.06 mGycm |
* CTDI | 6.74 mGy | 1.44 mGy |
Thumb | ||
Tube Voltage | 80 kV | 120 kV |
Tube current | 50 mA | 80 mA |
Tube rotation time | 0.28 s | 0.28 s |
Reconstructed slice thickness | 1.25 mm | 1.25 mm |
Field of View | 300 mm | 300 mm |
Collimation | 192 × 0.625 mm | 192 × 0.625 mm |
Dose length product | 156.45 mGycm | 19.58 mGycm |
CTDI | 13 mGy | 1.63 mGy |
Parameter | First Stage | Second Stage | Final Stage |
---|---|---|---|
Similarity Metric | (MSD/MI/NCC) * | (MSD/MI/NCC) * | (MSD/MI/NCC) * |
Regulariser | / | / | Bending energy |
Transform | Rigid | Affine | B-Spline |
Multi Resolution levels | 4 | 4 | 4 |
Number of histogram bins used for MI | 32 | 32 | 32 |
Sampler | Random | Random | Random |
Max iterations | 2000 | 1000 | 1000 |
Number of samples | 2000 | 2000 | 2000 |
Optimizer | Stochastic Gradient Descent | Stochastic Gradient Descent | Stochastic Gradient Descent |
Joint | Dice Score | FP | FN | Mean Surface Distance (mm) | Max Surface Distance (mm) | SD Surface Distance (mm) |
---|---|---|---|---|---|---|
Thumb | 0.90 ± 0.01 | 0.08 ± 0.02 | 0.14 ± 0.03 | 0.53 ± 0.05 | 4.89 ± 1.25 | 0.68 ± 0.05 |
Knee | 0.94 ± 0.02 | 0.05 ± 0.02 | 0.06 ± 0.02 | 0.42 ± 0.16 | 4.91 ± 1.13 | 0.66 ± 0.18 |
Thumb | * AUTO | ||
---|---|---|---|
X | Y | Z | |
Reader 1 | 0.99 | 0.99 | 0.99 |
Reader 2 | 0.95 | 0.94 | 0.99 |
Reader 3 | 0.92 | 0.94 | 0.99 |
Reader AVG | 0.95 | 0.97 | 0.99 |
Knee | X | Y | Z |
Reader 1 | 0.99 | 0.72 | 0.96 |
Reader 2 | 0.99 | 0.76 | 0.95 |
Reader 3 | 0.99 | 0.83 | 0.94 |
* Reader AVG | 0.99 | 0.82 | 0.96 |
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Keelson, B.; Buzzatti, L.; Ceranka, J.; Gutiérrez, A.; Battista, S.; Scheerlinck, T.; Van Gompel, G.; De Mey, J.; Cattrysse, E.; Buls, N.; et al. Automated Motion Analysis of Bony Joint Structures from Dynamic Computer Tomography Images: A Multi-Atlas Approach. Diagnostics 2021, 11, 2062. https://0-doi-org.brum.beds.ac.uk/10.3390/diagnostics11112062
Keelson B, Buzzatti L, Ceranka J, Gutiérrez A, Battista S, Scheerlinck T, Van Gompel G, De Mey J, Cattrysse E, Buls N, et al. Automated Motion Analysis of Bony Joint Structures from Dynamic Computer Tomography Images: A Multi-Atlas Approach. Diagnostics. 2021; 11(11):2062. https://0-doi-org.brum.beds.ac.uk/10.3390/diagnostics11112062
Chicago/Turabian StyleKeelson, Benyameen, Luca Buzzatti, Jakub Ceranka, Adrián Gutiérrez, Simone Battista, Thierry Scheerlinck, Gert Van Gompel, Johan De Mey, Erik Cattrysse, Nico Buls, and et al. 2021. "Automated Motion Analysis of Bony Joint Structures from Dynamic Computer Tomography Images: A Multi-Atlas Approach" Diagnostics 11, no. 11: 2062. https://0-doi-org.brum.beds.ac.uk/10.3390/diagnostics11112062