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Article
Peer-Review Record

Characteristics and Outcomes of Bloodstream Infections in a Tertiary-Care Pediatric Hematology–Oncology Unit: A 10-Year Study

by Davide Mattei 1, Valentina Baretta 1, Annarita Mazzariol 2, Laura Maccacaro 2, Rita Balter 1, Ada Zaccaron 1, Elisa Bonetti 1, Matteo Chinello 1, Virginia Vitale 1, Giulia Caddeo 1, Maria Pia Esposto 1, Vincenza Pezzella 1, Davide Gibellini 2, Gloria Tridello 1 and Simone Cesaro 1,*
Reviewer 1: Anonymous
Reviewer 3: Anonymous
Submission received: 23 December 2021 / Revised: 24 January 2022 / Accepted: 3 February 2022 / Published: 8 February 2022
(This article belongs to the Section Hematology)

Round 1

Reviewer 1 Report

I have attached a PDF file including my comments. The topic is important and the data outlined is interesting, there are several formatting issues.

Comments for author File: Comments.pdf

Author Response

Please see the attachment

Author Response File: Author Response.doc

Reviewer 2 Report

The incidence of BSI was screened over a very long period of 10 years. features of the unit, hygiene conditions may have changed.
It is unclear how long the patients received inpatient treatment.
Were all patients over the 10-year period included?
very small number of patients compared to this period.
the bed capacity of the unit etc. should be explained.
Did all patients have a central catheter?
What are the unit's blood culture protocol and indications?
Was a blood culture taken in all cases requiring hospitalization?

Author Response

Please see the attachment

Author Response File: Author Response.doc

Reviewer 3 Report

This interesting study evaluated the epidemiology, risk factors and clinical outcomes of BSI in a pediatric hemato-oncology unit. 

The study has been well conducted and the paper is well-written. It needs some minor spell-check of the microorganism names on table 2. 

No further comments.

Author Response

Please see the attachment

Round 2

Reviewer 2 Report

Author corrections are appropriate.
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