Biomimetic Collagen/Zn2+-Substituted Calcium Phosphate Composite Coatings on Titanium Substrates as Prospective Bioactive Layer for Implants: A Comparative Study Spin Coating vs. MAPLE
Abstract
:1. Introduction
2. Materials and Methods
2.1. Materials
2.2. Coll/Zn2+-CaPs Hydrogels: Preparation
2.3. Deposition Methods
2.3.1. Spin Coating
2.3.2. Matrix-Assisted Pulsed Laser Evaporation (MAPLE)
2.4. Structural and Morphological Analyses
2.5. In-Vitro Testing in Simulated Body Fluids (SBF)
2.6. Cell Viability
3. Results and Discussion
3.1. Coll/Zn2+-CaPs Biocomposite Coatings: Structural and Morphological Characterization
3.1.1. FTIR
3.1.2. IR Microscopy
3.1.3. SEM
3.2. In-Vitro SBF Assay of Coll/Zn2+-CaPs Biocomposite Coatings
3.2.1. FTIR
3.2.2. SEM and EDAX
3.3. Cytological Assay of Coll/Zn2+-CaPs Biocomposite Coatings
4. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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Ionic Species | Na+ | K+ | Mg2+ | Ca2+ | Cl− | HCO3− | HPO42− | SO42− |
---|---|---|---|---|---|---|---|---|
Concentration of the ionic species (mmol/L) | 142.0 | 5.0 | 1.5 | 2.5 | 148.8 | 4.2 | 1.0 | 0.5 |
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Neacsu, I.A.; Arsenie, L.V.; Trusca, R.; Ardelean, I.L.; Mihailescu, N.; Mihailescu, I.N.; Ristoscu, C.; Bleotu, C.; Ficai, A.; Andronescu, E. Biomimetic Collagen/Zn2+-Substituted Calcium Phosphate Composite Coatings on Titanium Substrates as Prospective Bioactive Layer for Implants: A Comparative Study Spin Coating vs. MAPLE. Nanomaterials 2019, 9, 692. https://0-doi-org.brum.beds.ac.uk/10.3390/nano9050692
Neacsu IA, Arsenie LV, Trusca R, Ardelean IL, Mihailescu N, Mihailescu IN, Ristoscu C, Bleotu C, Ficai A, Andronescu E. Biomimetic Collagen/Zn2+-Substituted Calcium Phosphate Composite Coatings on Titanium Substrates as Prospective Bioactive Layer for Implants: A Comparative Study Spin Coating vs. MAPLE. Nanomaterials. 2019; 9(5):692. https://0-doi-org.brum.beds.ac.uk/10.3390/nano9050692
Chicago/Turabian StyleNeacsu, Ionela Andreea, Laura Vasilica Arsenie, Roxana Trusca, Ioana Lavinia Ardelean, Natalia Mihailescu, Ion Nicolae Mihailescu, Carmen Ristoscu, Coralia Bleotu, Anton Ficai, and Ecaterina Andronescu. 2019. "Biomimetic Collagen/Zn2+-Substituted Calcium Phosphate Composite Coatings on Titanium Substrates as Prospective Bioactive Layer for Implants: A Comparative Study Spin Coating vs. MAPLE" Nanomaterials 9, no. 5: 692. https://0-doi-org.brum.beds.ac.uk/10.3390/nano9050692